ZFIN ID: ZDB-EXP-170209-4
Experiment Conditions Description: chemical treatment by environment: torin 1
chemical treatment by environment: torin 1
Name: chemical treatment by environment
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: torin 1
Synonyms: 1-[4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one, torin1
Definition: A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.
Ontology: ChEBI [CHEBI:84327]  ( EBI )
Publication: Shen et al., 2016