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ZFIN ID: ZDB-EXP-170131-3
Experiment Conditions Description: chemical treatment by environment: SL-327
chemical treatment by environment: SL-327
Name: chemical treatment by environment
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: SL-327
Synonyms: 3-amino-3-[(4-aminophenyl)sulfanyl]-2-[2-(trifluoromethyl)phenyl]acrylonitrile, 3-amino-3-[(4-aminophenyl)thio]-2-[2-(trifluoromethyl)phenyl]-2-propenenitrile, alpha-{amino[(4-aminophenyl)thio]methylene}-2-(trifluoromethyl)benzeneacetonitrile, SL 327, SL327
Definition: A nitrile that is acrylonitrile in which the hydrogen attached to the same carbon as the cyano group has been replaced by an o-(trifluoromethyl)phenyl group, while the remaining hydrogens of the ethenyl group have been replaced by amino and (4-aminophenyl)sulfanyl groups. The configuration of the double bond is not specified. It is an inhibitor of MEK1 and MEK2.
Ontology: Chebi [CHEBI:92211]
Publication: Shin et al., 2016