header logo image header logo text
Downloads Login
General Information
ZFIN ID: ZDB-EXP-161027-3
Experiment Conditions Description: chemical treatment: mycophenolic acid
chemical treatment: mycophenolic acid
Name: chemical treatment
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: mycophenolic acid
Synonyms: (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid, (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid, acide mycophenolique, acido micofenolico, acidum mycophenolicum, Micofenolico acido, Mycophenolate, mycophenolic acid, Mycophenolsaeure
Definition: A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.
Ontology: Chebi [CHEBI:168396]
Publication: Cox et al., 2016