ZFIN ID: ZDB-EXP-121213-7
Experiment Conditions Description: constant light, chemical treatment: 8-bromo-3',5'-cyclic GMP
constant light
Name: constant light
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000150]
chemical treatment: 8-bromo-3',5'-cyclic GMP
Name: chemical treatment
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: 8-bromo-3',5'-cyclic GMP
Synonyms: 8-Br-cGMP, 8-Br-Cyclic GMP, 8-Bromo-cgmp, 8-Bromocyclic GMP, 8-Bromocyclic guanosine monophosphate, 8-bromoguanosine 3',5'-(hydrogen phosphate), 8-Bromoguanosine 3',5'-cyclic monophosphate, 8-Bromoguanosine 3',5'-monophosphate
Definition: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.
Ontology: ChEBI [CHEBI:64108]  ( EBI )
Publication: Nakao et al., 2012