Community Action Needed: Please respond to the NIH RFI
Gene

dhx8

ID
ZDB-GENE-050809-39
Name
DEAH (Asp-Glu-Ala-His) box polypeptide 8
Symbol
dhx8 Nomenclature History
Previous Names
  • im:7153552
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to enable RNA binding activity. Acts upstream of or within cell division; mRNA splicing, via endonucleolytic cleavage and ligation; and primitive hemopoiesis. Located in nucleus. Is expressed in brain; midbrain; and pronephric duct. Orthologous to human DHX8 (DEAH-box helicase 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from English et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dhx8 Human Ortholog
No data available
Associated With dhx8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
Domain IPR001650 Helicase, C-terminal
Domain IPR003029 S1 domain
Domain IPR007502 Helicase-associated domain
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR011709 Domain of unknown function DUF1605
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR022967 RNA-binding domain, S1
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length DEAD/DEAH box helicase domain DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site Domain of unknown function DUF1605 Helicase-associated domain Helicase, C-terminal Helicase superfamily 1/2, ATP-binding domain Nucleic acid-binding, OB-fold P-loop containing nucleoside triphosphate hydrolase RNA-binding domain, S1 S1 domain
UniProtKB:A0A286Y8Y8 1238
UniProtKB:E7F7E3 1210
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations