Gene

chd1

ID
ZDB-GENE-030131-7120
Name
chromodomain helicase DNA binding protein 1
Symbol
chd1 Nomenclature History
Previous Names
  • fc26h11
  • fk85d05
  • si:dkey-106m21.4
  • wu:fc26h11
  • wu:fk85d05 (1)
  • zgc:173506
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable several functions, including ATP binding activity; DNA binding activity; and DNA helicase activity. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and prostate cancer. Orthologous to human CHD1 (chromodomain helicase DNA binding protein 1).
Genome Resources
Note
corresponds to ENSDARG00000014878, Chr10
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chd1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Pilarowski-Bjornsson syndrome 617682
Associated With chd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023779 Chromo domain, conserved site
Domain IPR000330 SNF2-related domain
Domain IPR000953 Chromo/chromo shadow domain
Domain IPR001650 Helicase, C-terminal
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR023780 Chromo domain
Domain IPR025260 Domain of unknown function DUF4208
Domain IPR040793 CDH1/2, SANT-Helical linker 1
Homologous_superfamily IPR016197 Chromo-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR038718 SNF2-like, N-terminal domain superfamily
Domain Details Per Protein
Protein Length CDH1/2, SANT-Helical linker 1 Chromo/chromo shadow domain Chromo domain Chromo domain, conserved site Chromo-like domain superfamily Domain of unknown function DUF4208 Helicase, C-terminal Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase SNF2-like, N-terminal domain superfamily SNF2-related domain
UniProtKB:A0A0R4IAE4 1777
UniProtKB:A0A0R4IC05 1693
UniProtKB:A8WGJ4 153
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations