Gene Ontology (GO) terms are derived from dynamic controlled vocabularies, or ontologies, produced by the
Gene Ontology Consortium to describe the roles of genes and gene
products in all organisms. The Gene Ontology Consortium has developed and continues to expand ontologies of
terms that define the molecular functions, biological
processes, and cellular components:
- Molecular Function: Terms that describe what a gene product does at a
biochemical level.
- Biological Process: Broad biological processes that are accomplished by
ordered assemblies of molecular functions.
- Cellular Component: Subcellular structures, locations, and macromolecular
complexes in the cell where a gene product is found.
GO Annotations in ZFIN
The GO annotations in ZFIN are divided into four columns:
Ontology
|
From which ontology the GO term is derived (Molecular Function, Biological Process, or Cellular
Component).
|
GO Term
|
The Gene Ontology term. The GO term is linked to the QuickGO ontology browser entry.
|
Evidence
|
The evidence code supporting the
annotation of the GO term to the gene product. The evidence code in the table is linked to a list of
descriptions, criteria, and use of each evidence code.
|
Reference
|
A link to the reference in ZFIN from which the annotation was derived.
|