Transgenic Construct
Tg(BMPRE-AAV.Mlp:mKOFP2)
- ID
- ZDB-TGCONSTRCT-110310-2
- Name
- Tg(BMPRE-AAV.Mlp:mKOFP2)
- Previous Names
- Type
- engineered_plasmid
- Regulatory Regions
- None
- Coding Sequences
- [Em λ][Ex λ]
- Fpbase:mKO2
- Contains Sequences
- Note
-
This construct utilizes the 84bp BMP Response Element (BRE) derived from mouse Id1 promoter, containing multiple short Smad-binding sites, and the Adeno-associated virus (AAV) major late promoter (mlp) driving expression of destabilized mKO2 with a C-terminal PEST domain from zebrafish Notch3 to facilitate rapid degradation by means of ubiquitinylation.
Plasmid Map
None
Genomic Features
That Utilize Tg(BMPRE-AAV.Mlp:mKOFP2) Construct
| Genomic Feature | Affected Genomic Regions |
|---|---|
| mw40Tg |
Transgenics
That Utilize Tg(BMPRE-AAV.Mlp:mKOFP2) Construct
| Fish | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|
| mw40Tg |
|
3 figures
from
2 publications
|
|
| mw40Tg/+ (AB) |
|
Sequence Information
Other Construct Pages
None
Citations