Transgenic Construct

Tg(actb2:EGFP-Hsa.ETV6-Hsa.RUNX1)

ID
ZDB-TGCONSTRCT-070523-3
Name
Tg(actb2:EGFP-Hsa.ETV6-Hsa.RUNX1)
Previous Names
  • ZBA-EGFP-TA (1)
  • Tg(actb2:EGFP-ETV6-RUNX1)
  • Tg(actb2:EGFP-Hsa.ETV6-RUNX1)
  • Tg(bactin:EGFP-ETV6-RUNX1)
Type
engineered_plasmid
Regulatory Regions
Coding Sequences
[Em λ][Ex λ]
Fpbase:EGFP
Contains Sequences
None
Note
This transgenic construct uses the zebrafish beta actin promoter to drive expression of a fusion product EGFP with the Human ETV6 and RUNX1 genes, also refered to as TEL-AML1 fustion associated with lymphoblastic leukemia (ALL).
Plasmid Map
None
Genomic Features
That Utilize Tg(actb2:EGFP-Hsa.ETV6-Hsa.RUNX1) Construct
Genomic Feature Affected Genomic Regions
nci3Tg
nj2Tg
Transgenics
That Utilize Tg(actb2:EGFP-Hsa.ETV6-Hsa.RUNX1) Construct
Fish Affected Genomic Regions Phenotype Gene Expression
nci3Tg
Fig. 4 from Sabaawy et al., 2006
nj2Tg/+ (AB)
Sequence Information
Other Construct Pages
None
Citations