TALEN

TALEN1-ezh2

ID
ZDB-TALEN-171114-1
Name
TALEN1-ezh2
Previous Names
None
Target
Target Sequence 1
5' - CCTGTTTGCTGGAGGCGGCG - 3'
Target Sequence 2
5' - TGAGCTGCCGCAGCCGCATG - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
ul2 ezh2
Expression
Gene expression in Wild Types + TALEN1-ezh2
No data available
Phenotype
Phenotype resulting from TALEN1-ezh2
No data available
Phenotype of all Fish created by or utilizing TALEN1-ezh2
Phenotype Fish Conditions Figures
exocrine pancreas decreased size, abnormal ezh2ul2/ul2 standard conditions Fig. S4 from Dupret et al., 2017
pancreas cell apoptotic, abnormal ezh2ul2/ul2 standard conditions Fig. 4 from Dupret et al., 2017
whole organism decreased life span, abnormal ezh2ul2/ul2 standard conditions Fig. 7 from Völkel et al., 2019
Fig. 4 from Dupret et al., 2017
spinal cord regeneration process quality, abnormal ezh2ul2/ul2 resection: spinal cord Fig. 7 from Dupret et al., 2017
eye phox2bb expression mislocalised, abnormal ezh2ul2/ul2 standard conditions Fig. 5 from Dupret et al., 2017
apoptotic process increased occurrence, abnormal ezh2ul2/ul2 standard conditions Fig. 4 from Dupret et al., 2017
whole organism dead, abnormal ezh2ul2/ul2 standard conditions Fig. 4 from Dupret et al., 2017
histone methyltransferase activity decreased process quality, abnormal ezh2ul2/ul2 standard conditions Fig. 7 from Dupret et al., 2017
intestinal epithelium morphology, abnormal ezh2ul2/ul2 standard conditions Fig. 4 from Dupret et al., 2017
intestine cell apoptotic, abnormal ezh2ul2/ul2 standard conditions Fig. 4 from Dupret et al., 2017
intestinal bulb epithelium morphology, abnormal ezh2ul2/ul2 standard conditions Fig. S3 from Dupret et al., 2017
exocrine pancreas prss1 expression decreased amount, abnormal ezh2ul2/ul2 standard conditions Fig. 6 from Dupret et al., 2017
exocrine pancreas development disrupted, abnormal ezh2ul2/ul2 standard conditions Fig. 6 from Dupret et al., 2017
whole organism decreased life span, exacerbated ezh1ul3/ul3; ezh2ul2/ul2 standard conditions Fig. 7 from Völkel et al., 2019
whole organism decreased life span, abnormal ezh1ul3/ul3; ezh2ul2/ul2 standard conditions Fig. 7 from Völkel et al., 2019
Citations