ZFIN ID: ZDB-TALEN-170405-1
TALEN Name: TALEN1-stat3
Target: stat3 (1)
Source:
Target Sequence 1:
5' - TAACCTCTTACTCATCCTCCA - 3'
   
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Target Sequence 2:
5' - TTCTCCAACATCTTCATCT - 3'
   
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  (Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.)
TARGET LOCATION
No data available
CONSTRUCTS WITH SEQUENCES FROM TALEN1-stat3 No data available
GENOMIC FEATURES CREATED WITH TALEN1-stat3
Genomic Feature Affected Genomic Regions    
stl27 stat3    
stl28 stat3    
GENE EXPRESSION
Gene expression in Wild Types + TALEN1-stat3 No data available
PHENOTYPE
Phenotype resulting from TALEN1-stat3
No data available

Phenotype of all Fish created by or utilizing TALEN1-stat3
Phenotype Fish Conditions Figures
notochord cell decreased length, abnormal stat3stl27/stl27 standard conditions Fig. 4 with image from Liu et al., 2017
neuromast stat3 expression decreased amount, abnormal stat3stl27/stl27 standard conditions Fig. 1 with image from Liu et al., 2017
notochord cell increased area, abnormal stat3stl27/stl27 standard conditions Fig. 4 with image from Liu et al., 2017
whole organism il6 expression increased amount, abnormal stat3stl27/stl27 standard conditions Fig. 2 with image from Liu et al., 2017
spinal cord bent, abnormal stat3stl27/stl27 standard conditions Fig. 2 with image from Liu et al., 2017
whole organism tnfa expression increased amount, abnormal stat3stl27/stl27 standard conditions Fig. 2 with image from Liu et al., 2017
somite 1 lateral region has fewer parts of type notochord cell, abnormal stat3stl27/stl27 standard conditions Fig. 7 with image from Liu et al., 2017
whole organism cell ab4-h3 labeling decreased distribution, abnormal stat3stl27/stl27 standard conditions Fig. 5 with image from Liu et al., 2017
whole organism stat3 expression decreased amount, abnormal stat3stl27/stl27 standard conditions Fig. 1 with imageFig. 9 with image from Liu et al., 2017
somite 2 lateral region has fewer parts of type notochord cell, abnormal stat3stl27/stl27 standard conditions Fig. 7 with image from Liu et al., 2017
blastomere stat3 expression decreased amount, abnormal stat3stl27/stl27 standard conditions Fig. 1 with image from Liu et al., 2017
mitotic cell cycle increased duration, abnormal stat3stl27/stl27 standard conditions Fig. 6 with image from Liu et al., 2017
head stat3 expression decreased amount, abnormal stat3stl27/stl27 standard conditions Fig. 1 with image from Liu et al., 2017
cell population proliferation decreased occurrence, abnormal stat3stl27/stl27 standard conditions Fig. 5 with image from Liu et al., 2017
bone tissue decreased volume, abnormal stat3stl27/stl27 standard conditions Fig. 2 with image from Liu et al., 2017
notochord cell increased width, abnormal stat3stl27/stl27 standard conditions Fig. 4 with image from Liu et al., 2017
somite anterior-posterior axis decreased length, exacerbated stat3stl27/stl27 standard conditions Fig. 7 with image from Liu et al., 2017
whole organism cell decreased amount, abnormal stat3stl27/stl27 standard conditions Fig. 5 with image from Liu et al., 2017
bone mineralization decreased occurrence, abnormal stat3stl27/stl27 standard conditions Fig. 2 with image from Liu et al., 2017
somite adaxial cell decreased amount, exacerbated stat3stl27/stl27 standard conditions Fig. 7 with image from Liu et al., 2017
whole organism decreased life span, abnormal stat3stl27/stl27 standard conditions Fig. 2 with image from Liu et al., 2017
whole organism cdc25b expression decreased amount, abnormal stat3stl27/stl27 standard conditions Fig. 9 with image from Liu et al., 2017
whole organism decreased life span, abnormal stat3stl27/stl27 standard conditions Fig. 2 with image from Liu et al., 2017
notochord cell shape, abnormal stat3stl27/stl27 standard conditions Fig. 4 with image from Liu et al., 2017
notochord decreased length, abnormal stat3stl27/stl27 standard conditions Fig. 3 with imageFig. 9 with image from Liu et al., 2017
whole organism decreased length, abnormal stat3stl27/stl27 standard conditions Fig. 2 with image from Liu et al., 2017
mitotic cell cycle, embryonic decreased occurrence, abnormal stat3stl27/stl27 standard conditions Fig. 5 with image from Liu et al., 2017
whole organism decreased length, abnormal stat3stl27/stl27 standard conditions Fig. 2 with image from Liu et al., 2017
notochord decreased length, exacerbated stat3stl27/stl27 + MO1-stat3 standard conditions Fig. 3 with image from Liu et al., 2017
whole organism decreased length, abnormal stat3stl28/stl28 standard conditions Fig. 2 with image from Liu et al., 2017
mitotic cell cycle increased duration, abnormal stat3stl27 standard conditions Fig. 5 with image from Liu et al., 2017
notochord cell decreased length, abnormal stat3stl27 standard conditions Fig. 4 with image from Liu et al., 2017
somite adaxial cell decreased amount, abnormal stat3stl27 standard conditions Fig. 7 with image from Liu et al., 2017
whole organism cell ab4-h3 labeling decreased distribution, abnormal stat3stl27 standard conditions Fig. 5 with image from Liu et al., 2017
somite 1 lateral region has fewer parts of type notochord cell, abnormal stat3stl27 standard conditions Fig. 7 with image from Liu et al., 2017
whole organism cell decreased amount, abnormal stat3stl27 standard conditions Fig. 5 with image from Liu et al., 2017
notochord cell shape, abnormal stat3stl27 standard conditions Fig. 4 with image from Liu et al., 2017
cell population proliferation decreased occurrence, abnormal stat3stl27 standard conditions Fig. 5 with image from Liu et al., 2017
somite anterior-posterior axis decreased length, abnormal stat3stl27 standard conditions Fig. 7 with image from Liu et al., 2017
mitotic cell cycle, embryonic decreased occurrence, abnormal stat3stl27 standard conditions Fig. 5 with image from Liu et al., 2017
notochord cell increased area, abnormal stat3stl27 standard conditions Fig. 4 with image from Liu et al., 2017
notochord decreased length, abnormal stat3stl27 standard conditions Fig. 3 with image from Liu et al., 2017
notochord cell increased width, abnormal stat3stl27 standard conditions Fig. 4 with image from Liu et al., 2017
somite 2 lateral region has fewer parts of type notochord cell, abnormal stat3stl27 standard conditions Fig. 7 with image from Liu et al., 2017
eye fused with eye, abnormal stat3stl27/stl27 ; vangl2vu67/vu67 standard conditions Fig. 4 with image from Liu et al., 2017
eye adjacent to eye, abnormal stat3stl27/stl27 ; vangl2vu67/vu67 standard conditions Fig. 4 with image from Liu et al., 2017
eye fused with eye, abnormal stat3stl27/stl27 ; wnt11tz216/tz216 standard conditions Fig. 4 with image from Liu et al., 2017
eye adjacent to eye, abnormal stat3stl27/stl27 ; wnt11tz216/tz216 standard conditions Fig. 4 with image from Liu et al., 2017
eye fused with eye, abnormal vangl2vu67/vu67 ; stat3stl27/+ standard conditions Fig. 4 with image from Liu et al., 2017
eye adjacent to eye, abnormal vangl2vu67/vu67 ; stat3stl27/+ standard conditions Fig. 4 with image from Liu et al., 2017
eye fused with eye, abnormal wnt11tz216/tz216 ; stat3stl27/+ standard conditions Fig. 4 with image from Liu et al., 2017
eye adjacent to eye, abnormal wnt11tz216/tz216 ; stat3stl27/+ standard conditions Fig. 4 with image from Liu et al., 2017
OTHER TALEN1-stat3 TALEN PAGESNo links to external sites
CITATIONS (2)