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General Information
ZIRC
ZFIN ID: ZDB-TALEN-170314-2
TALEN Name: TALEN1-ahi1
Target: ahi1 (1)
Source:
Target Sequence 1:
5' - TGTCAGCAGAAAACCAGACAG - 3'
   
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Target Sequence 2:
5' - TCCTCCTTGAACTCCTCTACA - 3'
   
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  (Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.)
TARGET LOCATION
No data available
CONSTRUCTS WITH SEQUENCES FROM TALEN1-ahi1 No data available
GENOMIC FEATURES CREATED WITH TALEN1-ahi1
Genomic Feature Affected Genomic Regions    
lri46 ahi1    
lri47 ahi1    
lri53 ahi1    
GENE EXPRESSION
Gene expression in Wild Types + TALEN1-ahi1 No data available
PHENOTYPE
Phenotype resulting from TALEN1-ahi1
No data available

Phenotype of all Fish created by or utilizing TALEN1-ahi1
Phenotype Fish Conditions Figures
post-vent region curved ventral, abnormal ahi1lri46/lri46 standard conditions Fig. 1 with image from Lessieur et al., 2017
retinal cone cell has fewer parts of type retinal cone cell photoreceptor outer segment, abnormal ahi1lri46/lri46 standard conditions Fig. 4 with image from Lessieur et al., 2017
whole organism lacks all parts of type swim bladder, abnormal ahi1lri46/lri46 standard conditions Fig. 1 with image from Lessieur et al., 2017
retinal outer nuclear layer dorsal region decreased thickness, abnormal ahi1lri46/lri46 standard conditions Fig. 4 with image from Lessieur et al., 2017
photoreceptor outer segment layer dorsal region malformed, abnormal ahi1lri46/lri46 standard conditions Fig. 4 with image from Lessieur et al., 2017
retinal cone cell photoreceptor cell outer segment organization decreased process quality, abnormal ahi1lri46/lri46 standard conditions Fig. 3 with imageFig. 4 with imageFig. 5 with imageFig. 7 with image from Lessieur et al., 2017
posterior pronephric duct lacks all parts of type posterior pronephric duct motile cilium, abnormal ahi1lri46/lri46 standard conditions Fig. 2 with image from Lessieur et al., 2017
retinal cone cell development decreased process quality, abnormal ahi1lri46/lri46 standard conditions Fig. 3 with imageFig. 7 with image from Lessieur et al., 2017
retinal cone cell lacks all parts of type retinal cone cell photoreceptor outer segment, abnormal ahi1lri46/lri46 standard conditions Fig. 7 with image from Lessieur et al., 2017
retinal cone cell photoreceptor outer segment irregular spatial pattern, abnormal ahi1lri46/lri46 standard conditions Fig. 3 with image from Lessieur et al., 2017
pronephric duct cilium assembly decreased occurrence, abnormal ahi1lri46/lri46 standard conditions Fig. 2 with image from Lessieur et al., 2017
retinal cone cell photoreceptor disc membrane irregular spatial pattern, abnormal ahi1lri46/lri46 standard conditions Fig. 5 with image from Lessieur et al., 2017
retinal outer nuclear layer zpr-3 labeling mislocalised, abnormal ahi1lri46/lri46 standard conditions Fig. 6 with image from Lessieur et al., 2017
retinal cone cell photoreceptor outer segment decreased length, abnormal ahi1lri46/lri46 standard conditions Fig. 3 with imageFig. 5 with imageFig. 7 with image from Lessieur et al., 2017
retinal cone cell photoreceptor outer segment disorganized, abnormal ahi1lri46/lri46 standard conditions Fig. 3 with imageFig. 5 with image from Lessieur et al., 2017
eye photoreceptor cell photoreceptor connecting cilium cc2d2a expression decreased amount, abnormal ahi1lri46/lri46 standard conditions Fig. 9 with image from Lessieur et al., 2017
optokinetic behavior decreased process quality, abnormal ahi1lri46/lri46 ; cep290fh297/fh297 standard conditions Fig. 12 from Lessieur et al., 2019
whole organism decreased life span, abnormal ahi1lri46/lri46 ; cep290fh297/fh297 standard conditions text only from Lessieur et al., 2019
whole organism dead, abnormal ahi1lri46/lri46 ; cep290fh297/fh297 standard conditions text only from Lessieur et al., 2019
retinal cone cell cone photoreceptor outer segment decreased amount, abnormal cep290fh297/fh297 ; ahi1lri46/+ standard conditions Fig 9 with image from Lessieur et al., 2019
optokinetic behavior decreased process quality, abnormal cep290fh297/fh297 ; ahi1lri46/+ standard conditions Fig. 12 from Lessieur et al., 2019
retinal cone cell decreased amount, abnormal cep290fh297/fh297 ; ahi1lri46/+ standard conditions Fig 9 with image from Lessieur et al., 2019
photoreceptor inner segment layer zpr-3 labeling mislocalised, abnormal cep290fh297/fh297 ; ahi1lri46/+ standard conditions Fig 9 with image from Lessieur et al., 2019
OTHER TALEN1-ahi1 TALEN PAGES No links to external sites
CITATIONS (2)