PUBLICATION
Emotional behavior in aquatic organisms? Lessons from crayfish and zebrafish
- Authors
- de Abreu, M.S., Maximino, C., Banha, F., Anastácio, P.M., Demin, K.A., Kalueff, A.V., Soares, M.C.
- ID
- ZDB-PUB-191114-29
- Date
- 2019
- Source
- Journal of neuroscience research 98(5): 764-779 (Review)
- Registered Authors
- Kalueff, Allan V., Maximino, Caio
- Keywords
- aggressiveness, anxiety, crayfish, social preference, translational research, zebrafish
- MeSH Terms
-
- Aggression/psychology
- Animals
- Anxiety/psychology
- Astacoidea/physiology*
- Behavior, Animal/physiology*
- Emotions/physiology*
- Zebrafish/physiology*
- PubMed
- 31722127 Full text @ J. Neurosci. Res.
Citation
de Abreu, M.S., Maximino, C., Banha, F., Anastácio, P.M., Demin, K.A., Kalueff, A.V., Soares, M.C. (2019) Emotional behavior in aquatic organisms? Lessons from crayfish and zebrafish. Journal of neuroscience research. 98(5):764-779.
Abstract
Experimental animal models are a valuable tool to study the neurobiology of emotional behavior and mechanisms underlying human affective disorders. Mounting evidence suggests that various aquatic organisms, including both vertebrate (e.g., zebrafish) and invertebrate (e.g., crayfish) species, may be relevant to study animal emotional response and its deficits. Ideally, model organisms of disease should possess considerable genetic and physiological homology to mammals, display robust behavioral and physiological responses to stress, and should be sensitive to a wide range of drugs known to modulate stress and affective behaviors. Here, we summarize recent findings in the field of zebrafish- and crayfish-based tests of stress, anxiety, aggressiveness and social preference, and discuss further perspectives of using these novel model organisms in translational biological psychiatry. Outlining the remaining questions in this field, we also emphasize the need in further development and a wider use of crayfish and zebrafish models to study the pathogenesis of affective disorders.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping