ZFIN ID: ZDB-PUB-150418-4
Zebrafish as a model for leukemia and other hematopoietic disorders
Rasighaemi, P., Basheer, F., Liongue, C., Ward, A.C.
Date: 2015
Source: Journal of Hematology & Oncology   8: 29 (Review)
Registered Authors: Liongue, Clifford, Rasighaemi, Parisa, Ward, Alister
Keywords: none
MeSH Terms:
  • Animals
  • Disease Models, Animal*
  • Hematologic Diseases*
  • Hematopoiesis/physiology*
  • Humans
  • Leukemia*
  • Zebrafish*
PubMed: 25884214 Full text @ J. Hematol. Oncol.
Zebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides an overview of zebrafish hematopoiesis and describes its application as a model of leukemia and other hematopoietic disorders.