PUBLICATION
Zebrafish as a model for leukemia and other hematopoietic disorders
- Authors
- Rasighaemi, P., Basheer, F., Liongue, C., Ward, A.C.
- ID
- ZDB-PUB-150418-4
- Date
- 2015
- Source
- Journal of Hematology & Oncology 8: 29 (Review)
- Registered Authors
- Liongue, Clifford, Rasighaemi, Parisa, Ward, Alister
- Keywords
- none
- MeSH Terms
-
- Animals
- Disease Models, Animal*
- Hematologic Diseases*
- Hematopoiesis/physiology*
- Humans
- Leukemia*
- Zebrafish*
- PubMed
- 25884214 Full text @ J. Hematol. Oncol.
Citation
Rasighaemi, P., Basheer, F., Liongue, C., Ward, A.C. (2015) Zebrafish as a model for leukemia and other hematopoietic disorders. Journal of Hematology & Oncology. 8:29.
Abstract
Zebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides an overview of zebrafish hematopoiesis and describes its application as a model of leukemia and other hematopoietic disorders.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping