ZFIN ID: ZDB-PUB-150214-6
Zebrafish: A marvel of high-throughput biology for 21st century toxicology.
Bugel, S.M., Tanguay, R.L., Planchart, A.
Date: 2014
Source: Current environmental health reports 1: 341-352 (Review)
Registered Authors: Tanguay, Robert L.
Keywords: Zebrafish embryo model, environmental exposure, high-throughput screening, human health
MeSH Terms: none
PubMed: 25678986 Full text @ Curr Environ Health Rep
The evolutionary conservation of genomic, biochemical and developmental features between zebrafish and humans is gradually coming into focus with the end result that the zebrafish embryo model has emerged as a powerful tool for uncovering the effects of environmental exposures on a multitude of biological processes with direct relevance to human health. In this review, we highlight advances in automation, high-throughput (HT) screening, and analysis that leverage the power of the zebrafish embryo model for unparalleled advances in our understanding of how chemicals in our environment affect our health and wellbeing.