PUBLICATION
Fish proteome analysis: model organisms and non-sequenced species
- Authors
- Forné, I., Abián, J., and Cerdà, J.
- ID
- ZDB-PUB-091215-25
- Date
- 2010
- Source
- Proteomics 10(4): 858-872 (Review)
- Registered Authors
- Cerdà, Joan
- Keywords
- Aquaculture, Fish proteomics, LC-MS/MS, Non-model organism, Two-dimensional electrophoresis
- MeSH Terms
-
- Animals
- Fish Proteins/analysis*
- Fish Proteins/chemistry*
- Fish Proteins/physiology
- Fishes/physiology*
- Models, Animal
- Proteomics/methods*
- PubMed
- 19953554 Full text @ Proteomics
Citation
Forné, I., Abián, J., and Cerdà, J. (2010) Fish proteome analysis: model organisms and non-sequenced species. Proteomics. 10(4):858-872.
Abstract
In the last decade, proteomic technologies have been increasingly used in fish biology research. Proteomics has been applied primarily to investigate the physiology, development biology and the impact of contaminants in fish model organisms, such as zebrafish (Danio rerio), as well as in some commercial species produced in aquaculture, mainly salmonids and cyprinids. However, the lack of previous genetic information on most fish species has been a major drawback for a more general application of the different proteomic technologies currently available. Also, many teleosts of interest in biological research and with potential application in aquaculture hold unique physiological characteristics that can not be directly addressed from the study of small laboratory fish models. This review describes proteomic approaches that have been used to investigate diverse biological questions in model and non-model fish species. We will also evaluate the current possibilities to integrate fish proteomics with other "omic" approaches, as well as with additional complementary techniques, in order to address the future challenges in fish biology research.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping