PUBLICATION

The zebrafish (Danio rerio): a model system for cranial suture patterning

Authors
Quarto, N., and Longaker, M.T.
ID
ZDB-PUB-060323-12
Date
2005
Source
Cells, tissues, organs   181(2): 109-118 (Journal)
Registered Authors
Keywords
Osteogenesis, Cranial suture patterning, Biogenesis, Craniosynostosis
MeSH Terms
  • Animals
  • Body Patterning*
  • Cranial Sutures/anatomy & histology
  • Cranial Sutures/growth & development*
  • Models, Animal*
  • Osteogenesis*
  • Zebrafish/growth & development*
PubMed
16534205 Full text @ Cells Tissues Organs
Abstract
The zebrafish (Danio rerio) is an alluring model system currently used to study early embryonic development, organogenesis and gene functional analysis. However, few studies have been devoted to post-embryonic development. We have explored the possibility of using this organism to analyze how cranial suture patterning occurs. This study reports on the establishment of the zebrafish skull vault anatomy, calvarial osteogenesis, and cranial suture morphology. Our results demonstrate that the anatomy of the zebrafish cranial vault and cranial sutures is very similar to that of mammalian organisms. Indeed, the zebrafish represents a versatile and valuable model system for the study of the biogenesis of cranial sutures.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes