PUBLICATION
Developmental Expression of NPY/PYY Receptors zYb and zYc in Zebrafish
- Authors
- Mathieu, M., Trombino, S., Argenton, F., Larhammar, D., and Vallarino, M.
- ID
- ZDB-PUB-050518-10
- Date
- 2005
- Source
- Annals of the New York Academy of Sciences 1040: 399-401 (Journal)
- Registered Authors
- Argenton, Francesco, Larhammar, Dan
- Keywords
- receptors; neuropeptides; ontogeny; zebrafish; whole-mount in situ hybridization
- MeSH Terms
-
- Animals
- Gene Expression Regulation, Developmental/physiology*
- Neuropeptide Y/biosynthesis*
- Neuropeptide Y/genetics
- Receptors, Gastrointestinal Hormone/biosynthesis*
- Receptors, Gastrointestinal Hormone/genetics
- Zebrafish/embryology
- Zebrafish/genetics
- Zebrafish/metabolism*
- PubMed
- 15891072 Full text @ Ann N Y Acad Sci
Citation
Mathieu, M., Trombino, S., Argenton, F., Larhammar, D., and Vallarino, M. (2005) Developmental Expression of NPY/PYY Receptors zYb and zYc in Zebrafish. Annals of the New York Academy of Sciences. 1040:399-401.
Abstract
This study describes the developmental expression of zYb and zYc receptors in zebrafish. RT-PCR demonstrated that both mRNAs are present from 24-hour postfertilization (hpf) and that their expression increased during larval development. Whole-mount in situ hybridization showed zYb mRNA expression in the epithalamus (24 hpf), telencephalon, hypothalamus, rhombencephalon (24-96 hpf), mesencephalon (48-96 hpf), hatching gland, and otic vesicle (48-64 hpf). zYc mRNA is expressed in the epithalamus (24 and 96 hpf), telencephalon (48-96 hpf), spinal cord, notochord (64 hpf), and hatching gland (96 hpf). These results show that zYb and zYc receptors are expressed during ontogeny, suggesting a role for neuropeptide Y (NPY) and/or peptide YY (PYY) in organogenesis.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping