PUBLICATION
Lateral line: precocious phenotypes and planar polarity
- Authors
- Whitfield, T.T.
- ID
- ZDB-PUB-050127-2
- Date
- 2005
- Source
- Current biology : CB 15(2): R67-70 (Review)
- Registered Authors
- Whitfield, Tanya T.
- Keywords
- none
- MeSH Terms
-
- Animals
- Body Patterning/physiology*
- Cell Differentiation/physiology
- Gene Expression Regulation, Developmental*
- Intracellular Signaling Peptides and Proteins
- Mechanoreceptors/physiology*
- Morphogenesis*
- Neuroglia/physiology
- Neurons/physiology
- Nuclear Proteins
- Phenotype*
- Protein Tyrosine Phosphatases
- Time Factors
- Trans-Activators/metabolism
- Zebrafish/embryology*
- Zebrafish Proteins
- PubMed
- 15668161 Full text @ Curr. Biol.
Citation
Whitfield, T.T. (2005) Lateral line: precocious phenotypes and planar polarity. Current biology : CB. 15(2):R67-70.
Abstract
Work on zebrafish mutants that develop supernumerary neuromasts in the lateral line has revealed an inhibitory mechanism, mediated by glial cells, that represses newly identified precursors of secondary neuromasts, ensuring successive waves of neuromast production occur on time. The alignment of hair cells in neuromasts corresponds to the timing of these waves.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping