PUBLICATION

Lateral line: precocious phenotypes and planar polarity

Authors
Whitfield, T.T.
ID
ZDB-PUB-050127-2
Date
2005
Source
Current biology : CB   15(2): R67-70 (Review)
Registered Authors
Whitfield, Tanya T.
Keywords
none
MeSH Terms
  • Animals
  • Body Patterning/physiology*
  • Cell Differentiation/physiology
  • Gene Expression Regulation, Developmental*
  • Intracellular Signaling Peptides and Proteins
  • Mechanoreceptors/physiology*
  • Morphogenesis*
  • Neuroglia/physiology
  • Neurons/physiology
  • Nuclear Proteins
  • Phenotype*
  • Protein Tyrosine Phosphatases
  • Time Factors
  • Trans-Activators/metabolism
  • Zebrafish/embryology*
  • Zebrafish Proteins
PubMed
15668161 Full text @ Curr. Biol.
Abstract
Work on zebrafish mutants that develop supernumerary neuromasts in the lateral line has revealed an inhibitory mechanism, mediated by glial cells, that represses newly identified precursors of secondary neuromasts, ensuring successive waves of neuromast production occur on time. The alignment of hair cells in neuromasts corresponds to the timing of these waves.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping