PUBLICATION
Proneural, prosensory, antiglial: the many faces of neurogenins
- Authors
- Korzh, V. and Strähle, U.
- ID
- ZDB-PUB-030117-12
- Date
- 2002
- Source
- Trends in neurosciences 25(12): 603-605 (Review)
- Registered Authors
- Korzh, Vladimir, Strähle, Uwe
- Keywords
- glia; ngn1; zebrafish; neural plate; delta-notch signaling; gliogenesis; bHLH; xenopus; stem cell; rohon-beard
- MeSH Terms
-
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Biological Evolution
- Cell Differentiation/genetics*
- Nerve Tissue Proteins/physiology*
- Neuroglia/physiology
- Neurons, Afferent/physiology*
- Xenopus Proteins*
- PubMed
- 12446121 Full text @ Trends Neurosci.
Citation
Korzh, V. and Strähle, U. (2002) Proneural, prosensory, antiglial: the many faces of neurogenins. Trends in neurosciences. 25(12):603-605.
Abstract
Previous reports have linked Neurogenin 1 with the general promotion of neurogenesis and gliogenesis. A new study in zebrafish, supported by recent findings in Drosophila, has now challenged this idea by demonstrating that the activity of Neurogenin 1 is limited to activation of development of two classes of sensory neurons.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping