PUBLICATION

An ancestral whole-genome duplication may not have been responsible for the abundance of duplicated fish genes

Authors
Robinson-Rechavi, M., Marchand, O., Escriva, H., and Laudet, V.
ID
ZDB-PUB-010712-1
Date
2001
Source
Current biology : CB   11(12): R458-R459 (Review)
Registered Authors
Escriva, Hector, Laudet, Vincent, Marchand, Oriane, Robinson-Rechavi, Marc
Keywords
none
MeSH Terms
  • Animals
  • Fishes/classification
  • Fishes/genetics*
  • Gene Duplication*
  • Phylogeny*
PubMed
11448784 Full text @ Curr. Biol.
Abstract
Euteleost fishes have more duplicate genes than mammals [1,2] . The presence of additional Hox clusters in the zebrafish and observation of synteny groups have led to the hypothesis that a whole genome duplication at the origin of actinopterygian fish is responsible for these additional genes [3,4]. The alternative hypothesis ( Fig. 1) is that the abundance of duplicate genes is due to a high rate of local duplications, preceded or not by ancestral tetraploidization and massive gene loss. Our aim is to distinguish between these two hypotheses for the origin of duplicate genes in fish.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping