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ZFIN ID: ZDB-PUB-010511-9
Early efferent innervation of the zebrafish lateral line
Bricaud, O., Chaar, V., Dambly-Chaudiere, C., and Ghysen, A.
Date: 2001
Source: The Journal of comparative neurology 434(3): 253-261 (Journal)
Registered Authors: Bricaud, Olivier, Ghysen, Alain
Keywords: catecholaminergic diencephalic; rhombencephalic; octavolateral efferent neurons; tract of the postoptic commissure (TPOC)
MeSH Terms:
  • Animals
  • Dextrans
  • Fluoresceins
  • Hypothalamus/cytology*
  • Hypothalamus/growth & development
  • Indicators and Reagents
  • Larva/anatomy & histology
  • Mechanoreceptors/cytology*
  • Mechanoreceptors/growth & development
  • Neurons, Efferent/enzymology
  • Rhombencephalon/cytology*
  • Rhombencephalon/growth & development
  • Sense Organs/growth & development
  • Sense Organs/innervation*
  • Spinal Cord/cytology
  • Spinal Cord/growth & development
  • Tyrosine 3-Monooxygenase/analysis
  • Zebrafish/anatomy & histology*
PubMed: 11331527 Full text @ J. Comp. Neurol.
We examined the efferent innervation of the lateral line in zebrafish larvae. Three efferent nuclei were previously reported for the posterior line, two in the hindbrain and one in the ventral hypothalamus. Here we show that the same three nuclei innervate the anterior line as well. The rhombencephalic neurons innervate either the anterior or the posterior line. The diencephalic neurons seem to innervate both lines as well as the ear. The diencephalic efferents are labeled by anti-tyrosine hydroxylase antibodies and probably use dopamine as a transmitter. They are among the very first catecholaminergic neurons to differentiate in the brain and extend branches into the lateral line system almost as soon as the latter forms. We discuss possible functions of the rhombencephalic and diencephalic efferents.