PUBLICATION

Growth control in the ontogenetic and regenerating zebrafish fin

Authors
Johnson, S.L. and Bennett, P.
ID
ZDB-PUB-001115-6
Date
1999
Source
In The Zebrafish: Biology. H.W. Detrich, L.I. Zon, and M. Westerfield, eds. Methods Cell Biol.   59: 301-311 (Review)
Registered Authors
Bennett, Jr., Paul, Johnson, Stephen L.
Keywords
none
MeSH Terms
  • Animals
  • Regeneration/physiology*
  • Zebrafish/genetics
  • Zebrafish/physiology*
PubMed
9891366 Full text @ In The Zebrafish: Biology. H.W. Detrich, L.I. Zon, and M. Westerfield, eds. Methods Cell Biol.
Abstract
The growth and regeneration of the zebrafish fin provide yet another opportunity to exploit genetics to study important vertebrate problems. Mutants have been identified in zebrafish that affect the development of the embryonic fin, disrupt the normal growth relationship of fin and body, or disrupt the regeneration of the fin. Analysis of a regeneration mutation suggests that the developmental checkpoints that ensure developmental integrity in normal growth are absent in the early stages of regeneration. These stages correspond to the only time in fish developmental when differentiated bone cells divide.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping