ZFIN ID: ZDB-PERS-170208-12
Li, Mingyu
Email: limingyu@xmu.edu.cn
Affiliation: Mingyu Li Lab
Address: School of Pharmaceutical Sciences, Xiamen University, Xiangan nan Road, Xiangan Xiamen, China 361102


Li, Y., Liu, C., Bai, X., Li, M., Duan, C. (2023) FK506-binding protein 5 regulates cell quiescence-proliferation decision in zebrafish epithelium. FEBS letters. 597(14):1868-1879
Gao, S., Lin, X., Shi, Y., Zhou, H., Zheng, X., Li, M., Lin, T. (2023) A New Hypoglycemic Prenylated Indole Alkaloid N-Oxide from Endophytic Fungus Pallidocercospora crystalline. International Journal of Molecular Sciences. 24(10):
Kang, Q., Zheng, J., Jia, J., Xu, Y., Bai, X., Chen, X., Zhang, X.K., Wong, F.S., Zhang, C., Li, M. (2022) Disruption of the glucagon receptor increases glucagon expression beyond α-cell hyperplasia in zebrafish. The Journal of biological chemistry. 298(12):102665
Chen, Y., Jia, J., Zhao, Q., Zhang, Y., Huang, B., Wang, L., Tian, J., Huang, C., Li, M., Li, X. (2022) Novel Loss-of-Function Variant in HNF1a Induces β-Cell Dysfunction through Endoplasmic Reticulum Stress. International Journal of Molecular Sciences. 23(21):
Wang, W., Shi, Y., Liu, Y., Zhang, Y., Wu, J., Zhang, G., Che, Q., Zhu, T., Li, M., Li, D. (2022) Brasilterpenes A-E, Bergamotane Sesquiterpenoid Derivatives with Hypoglycemic Activity from the Deep Sea-Derived Fungus Paraconiothyrium brasiliense HDN15-135. Marine drugs. 20(5)
Zhu, C., Jiang, X., Tian, J., Chen, J., Lin, C., Wang, C., Tie, C., Li, M., Wu, C. (2022) Integrated approach toward absorption, distribution, metabolism, and excretion of Xiaoke pills in zebrafish based on UPLC-HRMS and DESI-MS techniques. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1200:123276
Xu, Y., Tian, J., Kang, Q., Yuan, H., Liu, C., Li, Z., Liu, J., Li, M. (2022) Knockout of Nur77 Leads to Amino Acid, Lipid, and Glucose Metabolism Disorders in Zebrafish. Frontiers in endocrinology. 13:864631
Liu, S.Z., Xu, G.X., He, F.M., Zhang, W.B., Wu, Z., Li, M.Y., Tang, X.X., Qiu, Y.K. (2022) New Sorbicillinoids with Tea Pathogenic Fungus Inhibitory Effect from Marine-Derived Fungus Hypocrea jecorina H8. Marine drugs. 20(3):
Jia, J., Kang, Q., Liu, S., Song, Y., Wong, F.S., Qiu, Y., Li, M. (2021) Artemether and aspterric acid induce pancreatic α cells to transdifferentiate into β cells in zebrafish. British journal of pharmacology. 179(9):1962-1977
Li, M., Rong, X., Lu, L., Li, Y., Yao, K., Ge, W., Duan, C. (2021) IGF-2 mRNA binding protein 2 regulates primordial germ cell development in zebrafish. General and comparative endocrinology. 313:113875
Xu, W., Zhou, M., Guo, Z., Lin, S., Li, M., Kang, Q., Xu, Y., Zhang, X., Xie, J. (2021) Impact of macroporous silica nanoparticles at sub-50nm on bio-behaviors and biosafety in drug-resistant cancer models. Colloids and surfaces. B, Biointerfaces. 206:111912
Bai, X., Jia, J., Kang, Q., Fu, Y., Zhou, Y., Zhong, Y., Zhang, C., Li, M. (2021) Integrated Metabolomics and Lipidomics Analysis Reveal Remodeling of Lipid Metabolism and Amino Acid Metabolism in Glucagon Receptor-Deficient Zebrafish. Frontiers in cell and developmental biology. 8:605979
Wu, Y., Ge, P., Xu, W., Li, M., Kang, Q., Zhang, X., Xie, J. (2020) Cancer-targeted and intracellular delivery of Bcl-2-converting peptide with functional macroporous silica nanoparticles for biosafe treatment. Materials science & engineering. C, Materials for biological applications. 108:110386
Kang, Q., Hu, M., Jia, J., Bai, X., Liu, C., Wu, Z., Chen, W., Li, M. (2020) Global Transcriptomic Analysis of Zebrafish Glucagon Receptor Mutant Reveals Its Regulated Metabolic Network. International Journal of Molecular Sciences. 21(3):
Chen, Z., Zhang, D., Yan, S., Hu, C., Huang, Z., Li, Z., Peng, S., Li, X., Zhu, Y., Yu, H., Lian, B., Kang, Q., Li, M., Zeng, Z., Zhang, X.K., Su, Y. (2019) SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway. European Journal of Medicinal Chemistry. 177:171-187
Dean, E.D., Li, M., Prasad, N., Wisniewski, S.N., Von Deylen, A., Spaeth, J., Maddison, L., Botros, A., Sedgeman, L.R., Bozadjieva, N., Ilkayeva, O., Coldren, A., Poffenberger, G., Shostak, A., Semich, M.C., Aamodt, K.I., Phillips, N., Yan, H., Bernal-Mizrachi, E., Corbin, J.D., Vickers, K.C., Levy, S.E., Dai, C., Newgard, C., Gu, W., Stein, R., Chen, W., Powers, A.C. (2017) Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation. Cell Metabolism. 25:1362-1373.e5
Li, M., Zhao, L., Page-McCaw, P.S., Chen, W. (2016) Zebrafish Genome Engineering Using the CRISPR-Cas9 System. Trends in genetics : TIG. 32(12):815-827
Li, M., Page-McCaw, P., Chen, W. (2016) FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation. Diabetes. 65(1):96-109
Li, M., Dean, E.D., Zhao, L., Nicholson, W.E., Powers, A.C., Chen, W. (2015) Glucagon receptor inactivation leads to α-cell hyperplasia in zebrafish. The Journal of endocrinology. 227:93-103
Varshney, G.K., Pei, W., LaFave, M.C., Idol, J., Xu, L., Gallardo, V., Carrington, B., Bishop, K., Jones, M., Li, M., Harper, U., Huang, S.C., Prakash, A., Chen, W., Sood, R., Ledin, J., Burgess, S.M. (2015) High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9. Genome research. 25(7):1030-42
Yin, L., Maddison, L.A., Li, M., Kara, N., LaFave, M.C., Varshney, G.K., Burgess, S.M., Patton, J.G., Chen, W. (2015) Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs. Genetics. 200(2):431-41
Li, M., Maddison, L.A., Page-McCaw, P., and Chen, W. (2014) Overnutrition induces β-cell differentiation through prolonged activation of β-cells in zebrafish larvae.. American journal of physiology. Endocrinology and metabolism. 306(7):E799-807
Maddison, L.A., Li, M., and Chen, W. (2014) Conditional gene-trap mutagenesis in zebrafish. Methods in molecular biology (Clifton, N.J.). 1101:393-411
Li, M., Maddison, L.A., Crees, Z., and Chen, W. (2013) Targeted Overexpression of CKI-Insensitive Cyclin-Dependent Kinase 4 Increases Functional β-Cell Number Through Enhanced Self-Replication in Zebrafish. Zebrafish. 10(2):170-6
Xiao, X., Li, M., Wang, K., Qin, Q., and Chen, X. (2011) Characterization of large yellow croaker (Pseudosciaena crocea) β-actin promoter supports β-actin gene as an internal control for gene expression modulation and its potential application in transgenic studies in fish. Fish & shellfish immunology. 30(4-5):1072-9
Wang, X., Lu, L., Li, Y., Li, M., Chen, C., Feng, Q., Zhang, C., and Duan, C. (2009) Molecular and functional characterization of two distinct IGF binding protein-6 genes in zebrafish. American journal of physiology. Regulatory, integrative and comparative physiology. 296(5):R1348-R1357
Li, M., Li, Y., Lu, L., Wang, X., Gong, Q., and Duan, C. (2009) Structural, gene expression, and functional analysis of the Fugu (Takifugu rubripes) insulin-like growth factor binding protein-4 gene. American journal of physiology. Regulatory, integrative and comparative physiology. 296(3):R588-R566