ZFIN Person: Knapen, Dries

ZFIN ID: ZDB-PERS-121116-5

Knapen, Dries

Email:	dries.knapen@ua.ac.be
URL:	http://www.zebrafishlab.be
Affiliation:	University of Antwerp zebrafishlab - Dries Knapen
Address:	University of Antwerp Department of Veterinary Sciences Campus Drie Eiken Universiteitsplein 1, UC.173 2610 Wilrijk Belgium
Country:	Belgium
Phone:	+3232652724
Fax:	+3232652729
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

van den Boom, R., Vergauwen, L., Koedijk, N., da Silva, K.M., Covaci, A., Knapen, D. (2023) Combined western diet and bisphenol A exposure induces an oxidative stress-based paraoxonase 1 response in larval zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 274:109758109758

Van Dingenen, I., Vergauwen, L., Haigis, A.C., Blackwell, B.R., Stacy, E., Villeneuve, D.L., Knapen, D. (2023) Deiodinase inhibition impairs the formation of the three posterior swim bladder tissue layers during early embryonic development in zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 261:106632106632

Braeuning, A., Balaguer, P., Bourguet, W., Carreras-Puigvert, J., Feiertag, K., Kamstra, J.H., Knapen, D., Lichtenstein, D., Marx-Stoelting, P., Rietdijk, J., Schubert, K., Spjuth, O., Stinckens, E., Thedieck, K., van den Boom, R., Vergauwen, L., von Bergen, M., Wewer, N., Zalko, D. (2023) Development of new approach methods for the identification and characterization of endocrine metabolic disruptors-a PARC project. Frontiers in toxicology. 5:12125091212509

Philippe, C., Vergauwen, L., Huyghe, K., De Boeck, G., Knapen, D. (2023) Chronic handling stress in zebrafish Danio rerio husbandry. Journal of Fish Biology. 103(2):367-377

Gölz, L., Baumann, L., Pannetier, P., Braunbeck, T., Knapen, D., Vergauwen, L. (2022) AOP Report: Thyroperoxidase Inhibition Leading to Altered Visual Function in Fish via Altered Retinal Layer Structure. Environmental toxicology and chemistry. 41(11):2632-2648

da Silva, K.M., Iturrospe, E., van den Boom, R., van de Lavoir, M., Robeyns, R., Vergauwen, L., Knapen, D., Cuykx, M., Covaci, A., van Nuijs, A.L.N. (2022) Lipidomics profiling of zebrafish liver through untargeted liquid chromatography-high resolution mass spectrometry. Journal of separation science. 45(15):2935-2945

Massei, R., Knapen, D., Covaci, A., Blust, R., Mayer, P., Vergauwen, L. (2021) Sublethal Effect Concentrations for Non-Polar Narcosis in the Zebrafish Embryo. Environmental toxicology and chemistry. 40(10):2802-2812

Stinckens, E., Vergauwen, L., Blackwell, B.R., Ankley, G.T., Villeneuve, D.L., Knapen, D. (2020) The effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish. Environmental science & technology. 54(10):6213-6223

Baumann, L., Segner, H., Ros, A., Knapen, D., Vergauwen, L. (2019) Thyroid Hormone Disruptors Interfere with Molecular Pathways of Eye Development and Function in Zebrafish. International Journal of Molecular Sciences. 20(7):

Gabriëls, I.J., Vergauwen, L., De Boevre, M., Van Dongen, S., Blust, R., De Saeger, S., Eeckhout, M., De Loose, M., Knapen, D. (2019) Optimizing the Use of Zebrafish Feeding Trials for the Safety Evaluation of Genetically Modified Crops. International Journal of Molecular Sciences. 20(6)

Michiels, E.D.G., Vergauwen, L., Lai, F.Y., Town, R.M., Covaci, A., van Nuijs, A.L.N., Van Cruchten, S.J., Knapen, D. (2018) Advancing the zebrafish embryo test for endocrine disruptor screening using micro-injection: ethinyl estradiol as a case study. Environmental toxicology and chemistry. 38(3):533-547

Verbueken, E., Bars, C., Ball, J.S., Periz-Stanacev, J., Marei, W.F.A., Tochwin, A., Gabriëls, I.J., Michiels, E.D.G., Stinckens, E., Vergauwen, L., Knapen, D., Van Ginneken, C.J., Van Cruchten, S.J. (2018) From mRNA Expression of Drug Disposition Genes to In Vivo Assessment of CYP-Mediated Biotransformation during Zebrafish Embryonic and Larval Development. International Journal of Molecular Sciences. 19(12)

Vergauwen, L., Cavallin, J.E., Ankley, G.T., Bars, C., Gabriëls, I.J., Michiels, E.D.G., Fitzpatrick, K.R., Periz-Stanacev, J., Randolph, E.C., Robinson, S.L., Saari, T.W., Schroeder, A.L., Stinckens, E., Swintek, J., Van Cruchten, S.J., Verbueken, E., Villeneuve, D.L., Knapen, D. (2018) Gene transcription ontogeny of hypothalamic-pituitary-thyroid axis development in early-life stage fathead minnow and zebrafish. General and comparative endocrinology. 266:87-100

Stinckens, E., Vergauwen, L., Ankley, G.T., Blust, R., Darras, V.M., Villeneuve, D.L., Witters, H., Volz, D.C., Knapen, D. (2018) An AOP-based alternative testing strategy to predict the impact of thyroid hormone disruption on swim bladder inflation in zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 200:1-12

Pype, C., Verbueken, E., Saad, M.A., Bars, C., Van Ginneken, C.J., Knapen, D., Van Cruchten, S.J. (2017) Antioxidants reduce reactive oxygen species but not embryotoxicity in the metabolic Danio rerio test (mDarT). Reproductive toxicology (Elmsford, N.Y.). 72:62-73

Michiels, E.D., Vergauwen, L., Hagenaars, A., Fransen, E., Dongen, S.V., Van Cruchten, S.J., Bervoets, L., Knapen, D. (2017) Evaluating Complex Mixtures in the Zebrafish Embryo by Reconstituting Field Water Samples: A Metal Pollution Case Study. International Journal of Molecular Sciences. 18(3)

Stinckens, E., Vergauwen, L., Schroeder, A.L., Maho, W., Blackwell, B.R., Witters, H., Blust, R., Ankley, G.T., Covaci, A., Villeneuve, D.L., Knapen, D. (2016) Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part II: Zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 173:204-17

Nelson, K.R., Schroeder, A.L., Ankley, G.T., Blackwell, B.R., Blanksma, C., Degitz, S.J., Flynn, K.M., Jensen, K.M., Johnson, R.D., Kahl, M.D., Knapen, D., Kosian, P.A., Milsk, R.Y., Randolph, E.C., Saari, T., Stinckens, E., Vergauwen, L., Villeneuve, D.L. (2016) Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part I: Fathead minnow. Aquatic toxicology (Amsterdam, Netherlands). 173:192-203

Houbrechts, A.M., Vergauwen, L., Bagci, E., Van Houcke, J., Heijlen, M., Kulemeka, B., Hyde, D.R., Knapen, D., Darras, V.M. (2016) Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function. Molecular and Cellular Endocrinology. 424:81-93

Vergauwen, L., Schmidt, S.N., Stinckens, E., Maho, W., Blust, R., Mayer, P., Covaci, A., Knapen, D. (2015) A high throughput passive dosing format for the Fish Embryo Acute Toxicity test. Chemosphere. 139:9-17

Pype, C., Verbueken, E., Saad, M.A., Casteleyn, C.R., Van Ginneken, C.J., Knapen, D., Van Cruchten, S.J. (2015) Incubation at 32.5°C and above causes malformations in the zebrafish embryo. Reproductive toxicology (Elmsford, N.Y.). 56:56-63

Bagci, E., Heijlen, M., Vergauwen, L., Hagenaars, A., Houbrechts, A.M., Esguerra, C.V., Blust, R., Darras, V.M., Knapen, D. (2015) Deiodinase Knockdown during Early Zebrafish Development Affects Growth, Development, Energy Metabolism, Motility and Phototransduction. PLoS One. 10:e0123285

Hagenaars, A., Stinckens, E., Vergauwen, L., Bervoets, L., Knapen, D. (2014) PFOS affects posterior swim bladder chamber inflation and swimming performance of zebrafish larvae. Aquatic toxicology (Amsterdam, Netherlands). 157C:225-235

Heijlen, M., Houbrechts, A.M., Bagci, E., Van Herck, S.L., Kersseboom, S., Esguerra, C.V., Blust, R., Visser, T.J., Knapen, D., and Darras, V.M. (2014) Knockdown of type 3 iodothyronine deiodinase severely perturbs both embryonic and early larval development in zebrafish. Endocrinology. 155(4):1547-1559

Hagenaars, A., Vergauwen, L., Benoot, D., Laukens, K., and Knapen, D. (2013) Mechanistic toxicity study of perfluorooctanoic acid in zebrafish suggests mitochondrial dysfunction to play a key role in PFOA toxicity. Chemosphere. 91(6):844-56

Vergauwen, L., Knapen, D., Hagenaars, A., and Blust, R. (2013) Hypothermal and hyperthermal acclimation differentially modulate cadmium accumulation and toxicity in the zebrafish. Chemosphere. 91(4):521-529

Vergauwen, L., Hagenaars, A., Blust, R., and Knapen, D. (2013) Temperature dependence of long-term cadmium toxicity in the zebrafish is not explained by liver oxidative stress: Evidence from transcript expression to physiology. Aquatic toxicology (Amsterdam, Netherlands). 126C:52-62

Vergauwen, L., Knapen, D., Hagenaars, A., De Boeck, G., and Blust, R. (2013) Assessing the impact of thermal acclimation on physiological condition in the zebrafish model. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 183(1):109-121

Hagenaars, A., Vergauwen, L., De Coen, W., and Knapen, D. (2011) Structure-activity relationship assessment of four perfluorinated chemicals using a prolonged zebrafish early life stage test. Chemosphere. 82(5):764-772

Vergauwen, L., Benoot, D., Blust, R., and Knapen, D. (2010) Long-term warm or cold acclimation elicits a specific transcriptional response and affects energy metabolism in zebrafish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 157(2):149-157

De Wit, M., Keil, D., Remmerie, N., Ven, K.V., Brandhof, E.J., Knapen, D., Witters, E., and Coen, W.D. (2008) Molecular targets of TBBPA in zebrafish analysed through integration of genomic and proteomic approaches. Chemosphere. 74(1):96-105

NON-ZEBRAFISH PUBLICATIONS