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Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-121009-2
Zhang, Jing-pu
Email: zhangjingpu@imb.pumc.edu.cn
URL:
Affiliation:
Address: Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences & Peking Union Medical College #1 Tian Tan Xi Li, Chongwen District Beijing China 100050
Country:
Phone: 0086 10 63186645
Fax:
Orcid ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Liu, Y., Zhang, X., Zhang, J., Hu, C. (2019) Construction of a Quantitative Structure Activity Relationship (QSAR) Model to Predict the Absorption of Cephalosporins in Zebrafish for Toxicity Study. Frontiers in pharmacology. 10:31
Zheng, Y.M., Chen, B., Jiang, J.D., Zhang, J.P. (2018) Syntaxin 1B Mediates Berberine's Roles in Epilepsy-Like Behavior in a Pentylenetetrazole-Induced Seizure Zebrafish Model. Frontiers in molecular neuroscience. 11:378
Liu, Y., Zhang, J., Hu, C. (2018) Validated LC-MS/MS method for simultaneous analysis of 21 cephalosporins in zebrafish for a drug toxicity study. Analytical biochemistry. 558:28-34
Chen, B., Zheng, Y.M., Zhang, J.P. (2018) Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish. Frontiers in endocrinology. 9:366
Han, Y., Zhang, J., Hu, C. (2018) A systematic toxicity evaluation of cephalosporins via transcriptomics in zebrafish and in silico ADMET studies. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 116(Pt B):264-271
Li, Y.C., Zhang, M.Q., Zhang, J.P. (2018) Opposite Effects of Two Human ATG10 Isoforms on Replication of a HCV Sub-genomic Replicon Are Mediated via Regulating Autophagy Flux in Zebrafish. Frontiers in cellular and infection microbiology. 8:109
Han, Y., Chen, B., Zhang, J., Hu, C. (2018) Cardiac safety evaluation in zebrafish and in silico ADME prediction of cephalosporins with an aminothiazoyl ring at the C-7 position. Toxicology and applied pharmacology. 347:33-44
Xiao, C., Han, Y., Liu, Y., Zhang, J., Hu, C.Q. (2018) Relationship between fluoroquinolone structure and neurotoxicity revealed by zebrafish neurobehavior. Chemical Research in Toxicology. 31(4):238-250
Han, Y., Zheng, Y., Zhang, J., Hu, C. (2018) Neurobehavioral Effects of Cephalosporins: Assessment of Locomotors Activity, Motor and Sensory Development in Zebrafish. Frontiers in pharmacology. 9:160
Qian, J., Han, Y., Li, J., Zhang, J., Hu, C. (2018) Toxic effect prediction of cefatirizine amidine sodium and its impurities by structure-toxicity relationship of cephalosporins. Toxicology in vitro : an international journal published in association with BIBRA. 46:137-147
Hu, Z.Y., Chen, B., Zhang, J.P., Ma, Y.Y. (2017) Up-regulation of autophagy-related gene 5 (ATG5) protects dopaminergic neurons in a zebrafish model of Parkinson's disease.. The Journal of biological chemistry. 292(44):18062-18074
Meng, X.H., Chen, B., Zhang, J.P. (2017) Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. International journal of biological sciences. 13:985-995
Han, Y., Qian, J., Zhang, J., Hu, C., Wang, C. (2017) Structure-toxicity relationship of cefoperazone and its impurities to developing zebrafish by transcriptome and Raman analysis. Toxicology and applied pharmacology. 327:39-51
Chen, B., Gao, Z.Q., Liu, Y., Zheng, Y.M., Han, Y., Zhang, J.P., Hu, C.Q. (2017) Embryo and Developmental Toxicity of Cefazolin Sodium Impurities in Zebrafish. Frontiers in pharmacology. 8:403
Zhang, F., Qin, W., Zhang, J.P., Hu, C.Q. (2015) Antibiotic toxicity and absorption in zebrafish using liquid chromatography-tandem mass spectrometry. PLoS One. 10:e0124805
Han, Y., Zhang, J.P., Qian, J.Q., Hu, C.Q. (2015) Cardiotoxicity evaluation of anthracyclines in zebrafish (Danio rerio). Journal of applied toxicology : JAT. 35(3):241-52
Ding, C.B., Zhao, Y., Zhang, J.P., Peng, Z.G., Song, D.Q., Jiang, J.D. (2015) A zebrafish model for subgenomic hepatitis C virus replication. International journal of molecular medicine. 35(3):791-7
Zhang, J., Qian, J., Tong, J., Zhang, D., and Hu, C.Q. (2013) Toxic Effects of Cephalosporins with Specific Functional Groups as Indicated by Zebrafish Embryo Toxicity Testing. Chemical Research in Toxicology. 26(8):1168-81
Zhao, Y., Qin, W., Zhang, J.P., Hu, Z.Y., Tong, J.W., Ding, C.B., Peng, Z.G., Zhao, L.X., Song, D.Q., and Jiang, J.D. (2013) HCV IRES-Mediated Core Expression in Zebrafish. PLoS One. 8(3):e56985
Hu, Z., Zhang, J., and Zhang, Q. (2011) Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis. Autophagy. 7(12):1514-1527
Ding, C.B., Zhang, J.P., Zhao, Y., Peng, Z.G., Song, D.Q., and Jiang, J.D. (2011) Zebrafish as a potential model organism for drug test against hepatitis C virus. PLoS One. 6(8):e22921

NON-ZEBRAFISH PUBLICATIONS