ZFIN ID: ZDB-PERS-120829-1
Kah, Olivier
Email: olivier.kah@univ-rennes1.fr
URL: http://www.irset.org/
Address: INSERM U1085 Research Institute in Health, Environment and Occupation Team NEED, Case 1302 Université de Rennes 1 Campus de Beaulieu 35 042 Rennes cedex, France
Phone: +33-2-23-23-67-65
Fax: +33-2-23-23-67-94


Chouchene, L., Kessabi, K., Gueguen, M.M., Kah, O., Pakdel, F., Messaoudi, I. (2022) Interference with zinc homeostasis and oxidative stress induction as probable mechanisms for cadmium-induced embryo-toxicity in zebrafish. Environmental science and pollution research international. 29(26):39578-39592
Kah, O. (2019) A 45-years journey within the reproductive brain of fish. General and comparative endocrinology. 288:113370
Vaillant, C., Gueguen, M.M., Feat, J., Charlier, T.D., Coumailleau, P., Kah, O., Brion, F., Pellegrini, E. (2019) Neurodevelopmental effects of natural and synthetic ligands of estrogen and progesterone receptors in zebrafish eleutheroembryos. General and comparative endocrinology. 288:113345
Cacialli, P., D'Angelo, L., Kah, O., Coumailleau, P., Gueguen, M.M., Pellegrini, E., Lucini, C. (2017) Neuronal expression of Brain Derived NeurotrophicFactor in the injured telencephalon of adult zebrafish. The Journal of comparative neurology. 526(4):569-582
Podechard, N., Chevanne, M., Fernier, M., Tête, A., Collin, A., Cassio, D., Kah, O., Lagadic-Gossmann, D., Sergent, O. (2017) Zebrafish larva as a reliable model for in vivo assessment of membrane remodeling involvement in the hepatotoxicity of chemical agents. Journal of applied toxicology : JAT. 37(6):732-746
Diotel, N., Mérot, Y., Coumailleau, P., Gueguen, M.M., Sérandour, A.A., Salbert, G., Kah, O. (2017) 5-hydroxymethylcytosine marks post-mitotic neural cells in the adult and developing vertebrate central nervous system. The Journal of comparative neurology. 525(3):478-497
Hinfray, N., Tebby, C., Garoche, C., Piccini, B., Bourgine, G., Aït-Aïssa, S., Kah, O., Pakdel, F., Brion, F. (2016) Additive effects of levonorgestrel and ethinylestradiol on brain aromatase (cyp19a1b) in zebrafish specific in vitro and in vivo bioassays. Toxicology and applied pharmacology. 307:108-114
Cano-Nicolau, J., Garoche, C., Hinfray, N., Pellegrini, E., Boujrad, N., Pakdel, F., Kah, O., Brion, F. (2016) Several synthetic progestins disrupt the glial cell specific-brain aromatase expression in developing zebra fish. Toxicology and applied pharmacology. 305:12-21
Cacialli, P., Gueguen, M.M., Coumailleau, P., D'Angelo, L., Kah, O., Lucini, C., Pellegrini, E. (2016) BDNF Expression in Larval and Adult Zebrafish Brain: Distribution and Cell Identification. PLoS One. 11:e0158057
Chouchene, L., Pellegrini, E., Gueguen, M.M., Hinfray, N., Brion, F., Piccini, B., Kah, O., Saïd, K., Messaoudi, I., Pakdel, F. (2016) Inhibitory effect of cadmium on estrogen signaling in zebrafish brain and protection by zinc. Journal of applied toxicology : JAT. 36(6):863-71
Cano-Nicolau, J., Vaillant, C., Pellegrini, E., Charlier, T.D., Kah, O., Coumailleau, P. (2016) Estrogenic Effects of Several BPA Analogs in the Developing Zebrafish Brain. Frontiers in neuroscience. 10:112
Diotel, N., Vaillant, C., Kah, O., Pellegrini, E. (2016) Mapping of Brain lipid binding protein (Blbp) in the brain of adult zebrafish, co-expression with aromatase B and links with proliferation. Gene expression patterns : GEP. 20(1):42-54
Vignet, C., Joassard, L., Lyphout, L., Guionnet, T., Goubeau, M., Le Menach, K., Brion, F., Kah, O., Chung, B.C., Budzinski, H., Bégout, M.L., Cousin, X. (2015) Exposures of zebrafish through diet to three environmentally relevant mixtures of PAHs produce behavioral disruptions in unexposed F1 and F2 descendant. Environmental science and pollution research international. 22(21):16371-83
Coumailleau, P., Pellegrini, E., Adrio, F., Diotel, N., Cano-Nicolau, J., Nasri, A., Vaillant, C., Kah, O. (2015) Aromatase, estrogen receptors and brain development in fish and amphibians. Biochimica et biophysica acta. Gene regulatory mechanisms. 1849(2):152-162
Fetter, E., Krauss, M., Brion, F., Kah, O., Scholz, S., Brack, W. (2014) Effect-directed analysis for estrogenic compounds in a fluvial sediment sample using transgenic cyp19a1b-GFP zebrafish embryos. Aquatic toxicology (Amsterdam, Netherlands). 154C:221-229
Pérez, M.R., Pellegrini, E., Cano-Nicolau, J., Gueguen, M.M., Menouer-Le Guillou, D., Merot, Y., Vaillant, C., Somoza, G.M., and Kah, O. (2013) Relationships between radial glial progenitors and 5-HT neurons in the paraventricular organ of adult zebrafish - potential effects of serotonin on adult neurogenesis. The European journal of neuroscience. 38(9):3292-301
Petersen, K., Fetter, E., Kah, O., Brion, F., Scholz, S., and Tollefsen, K.E. (2013) Transgenic (cyp19a1b-GFP) zebrafish embryos as a tool for assessing combined effects of oestrogenic chemicals. Aquatic toxicology (Amsterdam, Netherlands). 138-139:88-97
Diotel, N., Vaillant, C., Gabbero, C., Mironov, S., Fostier, A., Gueguen, M.M., Anglade, I., Kah, O., and Pellegrini, E. (2013) Effects of estradiol in adult neurogenesis and brain repair in zebrafish. Hormones and behavior. 63(2):193-207
Vosges, M., Kah, O., Hinfray, N., Chadili, E., Le Page, Y., Combarnous, Y., Porcher, J.M., and Brion, F. (2012) 17alpha-Ethinylestradiol and nonylphenol affect the development of forebrain GnRH neurons through an estrogen receptors-dependent pathway. Reproductive toxicology (Elmsford, N.Y.). 33(2):198-204
Brion, F., Le Page, Y., Piccini, B., Cardoso, O., Tong, S.K., Chung, B.C., and Kah, O. (2012) Screening Estrogenic Activities of Chemicals or Mixtures In Vivo Using Transgenic (cyp19a1b-GFP) Zebrafish Embryos. PLoS One. 7(5):e36069
Diotel, N., Rego, J.L., Anglade, I., Vaillant, C., Pellegrini, E., Gueguen, M.M., Mironov, S., Vaudry, H., and Kah, O. (2011) Activity and expression of steroidogenic enzymes in the brain of adult zebrafish. The European journal of neuroscience. 34(1):45-56
Servili, A., Le Page, Y., Leprince, J., Caraty, A., Escobar, S., Parhar, I.S., Seong, J.Y., Vaudry, H., and Kah, O. (2011) Organization of Two Independent Kisspeptin Systems Derived from Evolutionary-Ancient Kiss Genes in the Brain of Zebrafish. Endocrinology. 152(4):1527-1540
Diotel, N., Servili, A., Gueguen, M.M., Mironov, S., Pellegrini, E., Vaillant, C., Zhu, Y., Kah, O., and Anglade, I. (2011) Nuclear progesterone receptors are up-regulated by estrogens in neurons and radial glial progenitors in the brain of zebrafish. PLoS One. 6(11):e28375
Diotel, N., Vaillant, C., Gueguen, M.M., Mironov, S., Anglade, I., Servili, A., Pellegrini, E., and Kah, O. (2010) Cxcr4 and Cxcl12 expression in radial glial cells of the brain of adult zebrafish. The Journal of comparative neurology. 518(24):4855-4876
Vosges, M., Le Page, Y., Chung, B.C., Combarnous, Y., Porcher, J.M., Kah, O., and Brion, F. (2010) 17alpha-Ethinylestradiol disrupts the ontogeny of the forebrain GnRH system and the expression of brain aromatase during early development of zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 99(4):479-491
März, M., Chapouton, P., Diotel, N., Vaillant, C., Hesl, B., Takamiya, M., Lam, C.S., Kah, O., Bally-Cuif, L., and Strähle, U. (2010) Heterogeneity in progenitor cell subtypes in the ventricular zone of the zebrafish adult telencephalon. Glia. 58(7):870-888
Hanna, R.N., Daly, S.C., Pang, Y., Anglade, I., Kah, O., Thomas, P., and Zhu, Y. (2010) Characterization and Expression of the Nuclear Progestin Receptor in Zebrafish Gonads and Brain. Biology of reproduction. 82(1):112-122
Mouriec, K., Lareyre, J.J., Tong, S.K., Le Page, Y., Vaillant, C., Pellegrini, E., Pakdel, F., Chung, B.C., Kah, O., and Anglade, I. (2009) Early regulation of brain aromatase (cyp19a1b) by estrogen receptors during zebrafish development. Developmental dynamics : an official publication of the American Association of Anatomists. 238(10):2641-2651
Mouriec, K., Gueguen, M.M., Manuel, C., Percevault, F., Thieulant, M.L., Pakdel, F., and Kah, O. (2009) Androgens Upregulate cyp19a1b (Aromatase B) Gene Expression in the Brain of Zebrafish (Danio rerio) Through Estrogen Receptors. Biology of reproduction. 80(5):889-896
Tong, S.K., Mouriec, K., Kuo, M.W., Pellegrini, E., Gueguen, M.M., Brion, F., Kah, O., and Chung, B.C. (2009) A cyp19a1b-gfp (aromatase B) transgenic zebrafish line that expresses GFP in radial glial cells. Genesis (New York, N.Y. : 2000). 47(2):67-73
Kah, O., Pellegrini, E., Mouriec, K., Diotel, N., Anglade, I., Vaillant, C., Thieulant, M.L., Tong, S.K., Brion, F., Chung, B.C., and Pakdel, F. (2009) Oestrogens and neurogenesis: new functions for an old hormone. Lessons from the zebrafish. Journal de la Societe de biologie. 203(1):29-38
Le Page, Y., Menuet, A., Kah, O., and Pakdel, F. (2008) Characterization of a cis-acting element involved in cell-specific expression of the zebrafish brain aromatase gene. Molecular reproduction and development. 75(10):1549-1557
Kallivretaki, E., Eggen, R.I., Neuhauss, S.C., Kah, O., and Segner, H. (2007) The zebrafish, brain-specific, aromatase cyp19a2 is neither expressed nor distributed in a sexually dimorphic manner during sexual differentiation. Developmental dynamics : an official publication of the American Association of Anatomists. 236(11):3155-3166
Cheshenko, K., Brion, F., Le Page, Y., Hinfray, N., Pakdel, F., Kah, O., Segner, H., and Eggen, R.I. (2007) Expression of Zebra Fish Aromatase cyp19a and cyp19b Genes in Response to the Ligands of Estrogen Receptor and Aryl Hydrocarbon Receptor. Toxicological sciences : an official journal of the Society of Toxicology. 96(2):255-267
Pellegrini, E., Mouriec, K., Anglade, I., Menuet, A., Le Page, Y., Gueguen, M.M., Marmignon, M.H., Brion, F., Pakdel, F., and Kah, O. (2007) Identification of aromatase-positive radial glial cells as progenitor cells in the ventricular layer of the forebrain in zebrafish. The Journal of comparative neurology. 501(1):150-167
Le Page, Y., Scholze, M., Kah, O., and Pakdel, F. (2006) Assessment of xenoestrogens using three distinct estrogen receptors and the zebrafish brain aromatase gene in a highly responsive glial cell system. Environmental health perspectives. 114(5):752-758
Menuet, A., Pellegrini, E., Brion, F., Gueguen, M.M., Anglade, I., Pakdel, F., and Kah, O. (2005) Expression and estrogen-dependent regulation of the zebrafish brain aromatase gene. The Journal of comparative neurology. 485(4):304-320
Pellegrini, E., Menuet, A., Lethimonier, C., Adrio, F., Gueguen, M.M., Tascon, C., Anglade, I., Pakdel, F., and Kah, O. (2005) Relationships between aromatase and estrogen receptors in the brain of teleost fish. General and comparative endocrinology. 142(1-2):60-66
Menuet, A., Le Page, Y., Torres, O., Kern, L., Kah, O., and Pakdel, F. (2004) Analysis of the estrogen regulation of the zebrafish estrogen receptor (ER) reveals distinct effects of ERalpha, ERbeta1 and ERbeta2. Journal of molecular endocrinology. 32(3):975-986
Lethimonier, C., Madigou, T., Munoz-Cueto, J.A., Lareyre, J.J., and Kah, O. (2004) Evolutionary aspects of GnRHs, GnRH neuronal systems and GnRH receptors in teleost fish. General and comparative endocrinology. 135(1):1-16
Menuet, A., Pellegrini, E., Anglade, I., Blaise, O., Laudet, V., Kah, O., and Pakdel, F. (2002) Molecular characterization of three estrogen receptor forms in zebrafish: binding characteristics, transactivation properties, and tissue distributions. Biology of reproduction. 66(6):1881-1892