ZFIN Person: Howarth, Deanna

ZFIN ID: ZDB-PERS-101015-1

ZFIN ID: ZDB-PERS-101015-1

Howarth, Deanna

Email:	deannahowarth@gmail.com
URL:	http://www.linkedin.com/in/deannahowarth
Affiliation:
Address:	Sadler Research Laboratory Department of Medicine ~ Division of Liver Disease Department of Developmental and Regenerative Biology Mount Sinai School of Medicine One Gustave L. Levy Place New York, NY 10029-6574 USA
Country:
Phone:	212-241-0227
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Vacaru, A.M., Di Narzo, A.F., Howarth, D.L., Tsedensodnom, O., Imrie, D., Cinaroglu, A., Amin, S., Hao, K., Sadler, K.C. (2014) Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish. Disease models & mechanisms. 7:823-835

Howarth, D.L., Lindtner, C., Vacaru, A.M., Sachidanandam, R., Tsedensodnom, O., Vasilkova, T., Buettner, C., Sadler, K.C. (2014) Activating transcription factor 6 is necessary and sufficient for alcoholic Fatty liver disease in zebrafish. PLoS Genetics. 10:e1004335

Tsedensodnom, O., Vacaru, A.M., Howarth, D.L., Yin, C., and Sadler, K.C. (2013) Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease. Disease models & mechanisms. 6(5):1213-26

Howarth, D.L., Yin, C., Yeh, K., and Sadler, K.C. (2013) Defining hepatic dysfunction parameters in two models of Fatty liver disease in zebrafish larvae. Zebrafish. 10(2):199-210

Howarth, D.L., Vacaru, A.M., Tsedensodnom, O., Mormone, E., Nieto, N., Costantini, L.M., Snapp, E.L., and Sadler, K.C. (2012) Alcohol Disrupts Endoplasmic Reticulum Function and Protein Secretion in Hepatocytes. Alcoholism, clinical and experimental research. 36(1):14-23

Howarth, D.L., Passeri, M., and Sadler, K.C. (2011) Drinks Like a Fish: Using Zebrafish to Understand Alcoholic Liver Disease. Alcoholism, clinical and experimental research. 35(5):826-829

NON-ZEBRAFISH PUBLICATIONS
Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro.
Howarth DL, Hagey LR, Law SH, Ai N, Krasowski MD, Ekins S, Moore JT, Kollitz EM, Hinton DE, Kullman SW.
Aquat Toxicol. 2010 Jul 1;98(3):245-55.

Exposure to the synthetic FXR agonist GW4064 causes alterations in gene expression and sublethal hepatotoxicity in eleutheroembryo medaka (Oryzias latipes).
Howarth DL, Law SH, Law JM, Mondon JA, Kullman SW, Hinton DE.
Toxicol Appl Pharmacol. 2010 Feb 15;243(1):111-21.

Paralogous vitamin D receptors in teleosts: transition of nuclear receptor function.
Howarth DL, Law SH, Barnes B, Hall JM, Hinton DE, Moore L, Maglich JM, Moore JT, Kullman SW.
Endocrinology. 2008 May;149(5):2411-22. Erratum in: Endocrinology. 2008 Oct;149(10):5315.

Protective response of the Ah receptor to ANIT-induced biliary epithelial cell toxicity in see-through medaka.
Volz DC, Kullman SW, Howarth DL, Hardman RC, Hinton DE.
Toxicol Sci. 2008 Apr;102(2):262-77.