ZFIN Person: Sheets, Lavinia

ZFIN ID: ZDB-PERS-070606-1

Sheets, Lavinia

Email:	sheetsl@wustl.edu
URL:	http://sheetslab.net/
Affiliation:	Sheets Lab
Address:	Dept. Otolaryngology, Campus Box 8115 Washington Univ. School of Medicine 660 So. Euclid Ave. St. Louis, MO 63110
Country:	United States
Phone:
Fax:
ORCID ID:	0000-0001-5231-2450

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Newton, K.C., Kacev, D., Nilsson, S.R.O., Saettele, A.L., Golden, S.A., Sheets, L. (2023) Lateral line ablation by ototoxic compounds results in distinct rheotaxis profiles in larval zebrafish. Communications biology. 6:8484

Lee, D.S., Schrader, A., Bell, E., Warchol, M.E., Sheets, L. (2022) Evaluation of Cisplatin-Induced Pathology in the Larval Zebrafish Lateral Line. International Journal of Molecular Sciences. 23(22):

Saettele, A.L., Wong, H.C., Kindt, K.S., Warchol, M.E., Sheets, L. (2022) Prolonged Dexamethasone Exposure Enhances Zebrafish Lateral-Line Regeneration But Disrupts Mitochondrial Homeostasis and Hair Cell Function. Journal of the Association for Research in Otolaryngology : JARO. 23(6):683-700

Holmgren, M., Ravicz, M.E., Hancock, K.E., Strelkova, O., Kallogjeri, D., Indzhykulian, A.A., Warchol, M.E., Sheets, L. (2021) Mechanical overstimulation causes acute injury and synapse loss followed by fast recovery in lateral-line neuromasts of larval zebrafish. eLIFE. 10:

Holmgren, M., Sheets, L. (2021) Influence of Mpv17 on Hair-Cell Mitochondrial Homeostasis, Synapse Integrity, and Vulnerability to Damage in the Zebrafish Lateral Line. Frontiers in Cellular Neuroscience. 15:693375

Sheets, L., Holmgren, M., Kindt, K.S. (2021) How Zebrafish Can Drive the Future of Genetic-based Hearing and Balance Research. Journal of the Association for Research in Otolaryngology : JARO. 22(3):215-235

Holmgren, M., Sheets, L. (2021) Using the Zebrafish Lateral Line to Understand the Roles of Mitochondria in Sensorineural Hearing Loss. Frontiers in cell and developmental biology. 8:628712

Warchol, M.E., Schrader, A., Sheets, L. (2021) Macrophages Respond Rapidly to Ototoxic Injury of Lateral Line Hair Cells but Are Not Required for Hair Cell Regeneration. Frontiers in Cellular Neuroscience. 14:613246

Kindt, K.S., Sheets, L. (2018) Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish. Frontiers in cell and developmental biology. 6:114

Sheets, L., He, X.J., Olt, J., Schreck, M., Petralia, R.S., Wang, Y.X., Zhang, Q., Beirl, A., Nicolson, T., Marcotti, W., Trapani, J.G., Kindt, K.S. (2017) Enlargement of ribbons in zebrafish hair cells increases calcium currents, but disrupts afferent spontaneous activity and timing of stimulus onset. The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(26):6299-6313

Sebe, J.Y., Cho, S., Sheets, L., Rutherford, M.A., von Gersdorff, H., Raible, D.W. (2017) Ca²⁺-Permeable AMPARs Mediate Glutamatergic Transmission and Excitotoxic Damage at the Hair Cell Ribbon Synapse.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(25):6162-6175

Sheets, L. (2017) Excessive activation of ionotropic glutamate receptors induces apoptotic hair-cell death independent of afferent and efferent innervation. Scientific Reports. 7:41102

Lv, C., Stewart, W.J., Akanyeti, O., Frederick, C., Zhu, J., Santos-Sacchi, J., Sheets, L., Liao, J.C., Zenisek, D. (2016) Synaptic Ribbons Require Ribeye for Electron Density, Proper Synaptic Localization, and Recruitment of Calcium Channels. Cell Reports. 15(12):2784-95

Toro, C., Trapani, J.G., Pacentine, I., Maeda, R., Sheets, L., Mo, W., Nicolson, T. (2015) Dopamine Modulates the Activity of Sensory Hair Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(50):16494-16503

Sheets, L., Hagen, M.W., Nicolson, T. (2014) Characterization of Ribeye Subunits in Zebrafish Hair Cells Reveals That Exogenous Ribeye B-Domain and CtBP1 Localize to the Basal Ends of Synaptic Ribbons. PLoS One. 9:e107256

Sheets, L., Kindt, K.S., and Nicolson, T. (2012) Presynaptic CaV1.3 Channels Regulate Synaptic Ribbon Size and Are Required for Synaptic Maintenance in Sensory Hair Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(48):17273-17286

Sheets, L., Trapani, J.G., Mo, W., Obholzer, N., and Nicolson, T. (2011) Ribeye is required for presynaptic CaV1.3a channel localization and afferent innervation of sensory hair cells. Development (Cambridge, England). 138(7):1309-1319

Sheets, L., Ransom, D.G., Mellgren, E.M., Johnson, S.L., and Schnapp, B.J. (2007) Zebrafish Melanophilin Facilitates Melanosome Dispersion by Regulating Dynein. Current biology : CB. 17(20):1721-1734

Sheets, L. (2006) Zebrafish melanocytes as a model system to investigate intracellular transport regulation : a dissertation. Ph.D. Thesis. :135p

NON-ZEBRAFISH PUBLICATIONS