ZFIN ID: ZDB-PERS-020619-5
Kishi, Shuji
Email: kishi@scripps.edu
Affiliation: Kishi Lab
Address: Department of Cancer Biology Dana-Farber Cancer Institute Harvard Medical School Smith 970 44 Binney Street Boston, MA 02115 USA
Country: United States
Phone: 561-228-2959
Fax: 561-228-3059


Shi, Y., Liu, Z., Zhang, Q., Vallee, I., Mo, Z., Kishi, S., Yang, X.L. (2020) Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis. PLoS Biology. 18:e3000991
Sasaki, T., Lian, S., Khan, A., Llop, J.R., Samuelson, A.V., Chen, W., Klionsky, D.J., Kishi, S. (2017) Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase. Autophagy. 13(2):386-403
Song, Y., Shi, Y., Carland, T.M., Lian, S., Sasaki, T., Schork, N.J., Head, S.R., Kishi, S., Schimmel, P. (2016) p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 113(30):8460-5
Wei, N., Shi, Y., Truong, L.N., Fisch, K.M., Xu, T., Gardiner, E., Fu, G., Hsu, Y.S., Kishi, S., Su, A.I., Wu, X., Yang, X.L. (2014) Oxidative Stress Diverts tRNA Synthetase to Nucleus for Protection against DNA Damage. Molecular Cell. 56(2):323-32
Sasaki, T., Lian, S., Qi, J., Bayliss, P.E., Carr, C.E., Johnson, J.L., Guha, S., Kobler, P., Catz, S.D., Gill, M., Jia, K., Klionsky, D.J., Kishi, S. (2014) Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency. PLoS Genetics. 10:e1004409
Shi, Y., Xu, X., Zhang, Q., Fu, G., Mo, Z., Wang, G.S., Kishi, S., Yang, X.L. (2014) tRNA synthetase counteracts c-Myc to develop functional vasculature. eLIFE. 3:e02349
Kishi, S. (2014) Using zebrafish models to explore genetic and epigenetic impacts on evolutionary developmental origins of aging. Translational research : the journal of laboratory and clinical medicine. 163(2):123-135
Sasaki, T., and Kishi, S. (2013) Molecular and chemical genetic approaches to developmental origins of aging and disease in zebrafish. Biochimica et biophysica acta. Molecular basis of disease. 1832(9):1362-70
Sajish, M., Zhou, Q., Kishi, S., Valdez, D.M., Kapoor, M., Guo, M., Lee, S., Kim, S., Yang, X.L., and Schimmel, P. (2012) Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling. Nature Chemical Biology. 8(6):547-554
Xu, X., Yi Shi, Y., Zhang, H.-M., Swindell, E.C., Marshall, A.G., Guo, M., Kishi, S., Yang, X.-L. (2012) Unique domain appended to vertebrate tRNA synthetase is essential for vascular development. Nature communications. 3:681
Kishi, S. (2011) The search for evolutionary developmental origins of aging in zebrafish: A novel intersection of developmental and senescence biology in the zebrafish model system. Birth defects research. Part C, Embryo today : reviews. 93(3):229-248
Koshimizu, E., Imamura, S., Qi, J., Toure, J., Valdez, D.M., Carr, C.E., Hanai, J., and Kishi, S. (2011) Embryonic senescence and laminopathies in a progeroid zebrafish model. PLoS One. 6(3):e17688
Kishi, S., Slack, B.E., Uchiyama, J., and Zhdanova, I.V. (2009) Zebrafish as a genetic model in biological and behavioral gerontology: where development meets aging in vertebrates--a mini-review. Gerontology. 55(4):430-441
Kishi, S., Bayliss, P.E., Uchiyama, J., Koshimizu, E., Qi, J., Nanjappa, P., Imamura, S., Islam, A., Neuberg, D., Amsterdam, A., and Roberts, T.M. (2008) The identification of zebrafish mutants showing alterations in senescence-associated biomarkers. PLoS Genetics. 4(8):e1000152
Sidi, S., Sanda, T., Kennedy, R.D., Hagen, A.T., Jette, C.A., Hoffmans, R., Pascual, J., Imamura, S., Kishi, S., Amatruda, J.F., Kanki, J.P., Green, D.R., D'Andrea, A.A., and Look, A.T. (2008) Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3. Cell. 133(5):864-877
Imamura, S., Uchiyama, J., Koshimizu, E., Hanai, J., Raftopoulou, C., Murphey, R.D., Bayliss, P.E., Imai, Y., Burns, C.E., Masutomi, K., Gagos, S., Zon, L.I., Roberts, T.M., and Kishi, S. (2008) A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. PLoS One. 3(10):e3364
Hanai, J.I., Cao, P., Tanksale, P., Imamura, S., Koshimizu, E., Zhao, J., Kishi, S., Yamashita, M., Phillips, P.S., Sukhatme, V.P., and Lecker, S.H. (2007) The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. J. Clin. Invest.. 117(12):3940-3951
Tsai, S.B., Tucci, V., Uchiyama, J., Fabian, N.J., Lin, M.C., Bayliss, P.E., Neuberg, D.S., Zhdanova, I.V., and Kishi, S. (2007) Differential effects of genotoxic stress on both concurrent body growth and gradual senescence in the adult zebrafish. Aging Cell. 6(2):209-224
Yu, L., Tucci, V., Kishi, S., and Zhdanova, I.V. (2006) Cognitive aging in zebrafish. PLoS One. 1(1):e14
Imamura, S., and Kishi, S. (2005) Molecular cloning and functional characterization of zebrafish ATM. The international journal of biochemistry & cell biology. 37(5):1105-1116
Kishi, S. (2004) Functional Aging and Gradual Senescence in Zebrafish. Annals of the New York Academy of Sciences. 1019:521-526
Kishi, S., Uchiyama, J., Baughman, A.M., Goto, T., Lin, M.C., and Tsai, S.B. (2003) The zebrafish as a vertebrate model of functional aging and very gradual senescence. Experimental gerontology. 38(7):777-786