Morpholino

MO2-numb,numbl

ID

ZDB-MRPHLNO-110203-2

Name

MO2-numb,numbl

Previous Names

Targets

Sequence

5' - CAGGCTCTGACGCAGCTTATTCATC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Bresciana, et al. report translation blocking of both numb and numbl. The morpholino aligns 100% to numbl and 80% to numb.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-numb,numbl

Expressed Gene	Anatomy	Figures
egr2b	rhombomere 3 rhombomere 5	Fig. 3 from Bresciani et al., 2010
gata1a	erythroid lineage cell intermediate cell mass of mesoderm nucleate erythrocyte posterior lateral plate mesoderm	Fig. 3 , Fig. 5 from Bresciani et al., 2010
hbbe1.1	erythroid lineage cell intermediate cell mass of mesoderm	Fig. 3 from Bresciani et al., 2010
ikzf1	hematopoietic multipotent progenitor cell intermediate cell mass of mesoderm	Fig. 3 from Bresciani et al., 2010
myod1	segmental plate somite	Fig. 3 from Bresciani et al., 2010
spi1b	myeloid cell	Fig. 3 from Bresciani et al., 2010
tal1	hematopoietic multipotent progenitor cell posterior lateral plate mesoderm	Fig. 3 from Bresciani et al., 2010

Phenotype

Phenotype resulting from MO2-numb,numbl

No data available

Phenotype of all Fish created by or utilizing MO2-numb,numbl

Phenotype	Fish	Conditions	Figures
nucleate erythrocyte maturation disrupted, abnormal	WT + MO2-numb,numbl	standard conditions	Fig. 5 from Bresciani et al., 2010
nucleate erythrocyte immature, abnormal	WT + MO2-numb,numbl	standard conditions	Fig. 5 from Bresciani et al., 2010
nucleate erythrocyte composition, abnormal	WT + MO2-numb,numbl	standard conditions	Fig. 5 from Bresciani et al., 2010
erythroblast nucleus increased size, abnormal	WT + MO2-numb,numbl	standard conditions	Fig. 5 from Bresciani et al., 2010
erythroblast increased size, abnormal	WT + MO2-numb,numbl	standard conditions	Fig. 5 from Bresciani et al., 2010
whole organism viability, abnormal	sd2Tg + MO2-numb,numbl	standard conditions	text only from Bresciani et al., 2010
pericardium edematous, abnormal	sd2Tg + MO2-numb,numbl	standard conditions	text only from Bresciani et al., 2010
erythroid lineage cell decreased amount, abnormal	sd2Tg + MO2-numb,numbl	standard conditions	Fig. 2 , Fig. 4 from Bresciani et al., 2010
whole organism movement behavioral quality, abnormal	sd2Tg + MO2-numb,numbl	standard conditions	text only from Bresciani et al., 2010
blood circulation disrupted, abnormal	sd2Tg + MO2-numb,numbl	standard conditions	Fig. 2 , text only from Bresciani et al., 2010
nervous system decreased functionality, abnormal	sd2Tg + MO2-numb,numbl	standard conditions	text only from Bresciani et al., 2010

Citations