Morpholino

MO2-aplnrb

ID

ZDB-MRPHLNO-070531-1

Name

MO2-aplnrb

Previous Names

MO2-agtrl1b

Target

aplnrb (1)

Sequence

5' - CAGAGAAGTTGTTTGTCATGTGTCT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The morpholino has a 3 bp mismatch at the 3' end to agtrl1b sequences currently in the sequence databanks. The authors have verified the sequence of the morpholino.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-aplnrb

Expressed Gene	Anatomy	Figures
myl7	cardiac muscle cell	Fig. 2 from Scott et al., 2007
nkx2.5	heart primordium	Fig. 2 from Scott et al., 2007

Phenotype

Phenotype resulting from MO2-aplnrb

Phenotype	Fish	Figures
brain necrotic, abnormal	WT + MO2-aplnrb	Fig. 2 from Scott et al., 2007
embryo development disrupted, abnormal	WT + MO2-aplnrb	Fig. 2 from Scott et al., 2007
heart aplastic, abnormal	WT + MO2-aplnrb	Fig. 2 from Scott et al., 2007
heart development disrupted, abnormal	WT + MO2-aplnrb	Fig. 2 from Scott et al., 2007

Phenotype of all Fish created by or utilizing MO2-aplnrb

Phenotype	Fish	Conditions	Figures
heart aplastic, abnormal	WT + MO2-aplnrb	standard conditions	Fig. 2 from Scott et al., 2007
embryo development disrupted, abnormal	WT + MO2-aplnrb	standard conditions	Fig. 2 from Scott et al., 2007
brain necrotic, abnormal	WT + MO2-aplnrb	standard conditions	Fig. 2 from Scott et al., 2007
heart development disrupted, abnormal	WT + MO2-aplnrb	standard conditions	Fig. 2 from Scott et al., 2007
eye fused with eye, abnormal	WT + MO2-aplnrb + MO7-aplnra	chemical treatment: SB 431542	Fig. 2 from Deshwar et al., 2016
endodermal cell decreased amount, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 2 from Deshwar et al., 2016
endodermal cell sox32 expression decreased amount, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 2 from Deshwar et al., 2016
nodal signaling pathway decreased occurrence, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 2 from Deshwar et al., 2016
margin mespaa expression decreased amount, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 4 from Deshwar et al., 2016
larval heart development decreased process quality, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 3 from Deshwar et al., 2016
axial hypoblast noto expression decreased amount, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 2 from Deshwar et al., 2016
cardiac muscle cell myl7 expression decreased amount, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 3 from Deshwar et al., 2016
axial hypoblast gsc expression decreased amount, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 2 from Deshwar et al., 2016
margin mespab expression decreased amount, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 4 from Deshwar et al., 2016
endodermal cell sox32 expression decreased distribution, abnormal	WT + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 2 from Deshwar et al., 2016
eye fused with eye, abnormal	WT + MO1-tdgf1 + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 3 from Deshwar et al., 2016
larval heart development decreased process quality, abnormal	WT + MO1-tdgf1 + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 3 from Deshwar et al., 2016
cardiac muscle cell myl7 expression absent, abnormal	WT + MO1-tdgf1 + MO2-aplnrb + MO7-aplnra	standard conditions	Fig. 3 from Deshwar et al., 2016

Citations