ZFIN Lab: Horvath Lab

ZFIN ID: ZDB-LAB-200124-1

Horvath Lab

PI/Director:	Horvath, Rita
Contact Person:	Munro, Benjamin
Email:	bm550@cam.ac.uk
URL:
Address:	Department of Clinical Neurosciences, University of Cambridge John Van Geest Cambridge Centre for Brain Repair The ED Adrian Building Forvie Site, Robinson Way Cambridge CB2 0PY
Country:	United Kingdom
Phone:	+44 (0) 1223 762092
Fax:
Line Designation:	cu

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 2 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Munro, Benjamin Graduate Student

Mueller, Juliane Research Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Accogli, A., Lin, S.J., Severino, M., Kim, S.H., Huang, K., Rocca, C., Landsverk, M., Zaki, M., Al-Maawali, A., Srinivasan, V.M., Al-Thihli, K., Schaefer, G.B., Davis, M., Tonduti, D., Doneda, C., Marten, L.M., Mühlhausen, C., Gomez, M., Lamantea, E., Mena, R., Nizon, M., Procaccio, V., Begtrup, A., Telegrafi, A., Cui, H., Schulz, H.L., Mohr, J., Biskup, S., Loos, M.A., Aráoz, H.V., Salpietro, V., Keppen, L.D., Chitre, M., Petree, C., Raymond, L., Vogt, J., Swayer, L.B., Basinger, A.A., Pedersen, S.V., Pearson, T.S., Grange, D.K., Lingapp, L., McDunnah, P., Horvath, R., Cogne, B., Isidor, B., Hahn, A., Gripp, K., Jafarnejad, S.M., Ostergaard, E., Prada, C.E., Ghezzi, D., Gowda, V.K., Taylor, R.W., Sonenberg, N., Houlden, H., Sissler, M., Varshney, G.K., Maroofian, R. (2023) Clinical, neuroradiological and molecular characterization of mitochondrial threonyl-tRNA-synthetase (TARS2)-related disorder. Genetics in medicine : official journal of the American College of Medical Genetics. 25(11):100938

Van Haute, L., O'Connor, E., Díaz-Maldonado, H., Munro, B., Polavarapu, K., Hock, D.H., Arunachal, G., Athanasiou-Fragkouli, A., Bardhan, M., Barth, M., Bonneau, D., Brunetti-Pierri, N., Cappuccio, G., Caruana, N.J., Dominik, N., Goel, H., Helman, G., Houlden, H., Lenaers, G., Mention, K., Murphy, D., Nandeesh, B., Olimpio, C., Powell, C.A., Preethish-Kumar, V., Procaccio, V., Rius, R., Rebelo-Guiomar, P., Simons, C., Vengalil, S., Zaki, M.S., Ziegler, A., Thorburn, D.R., Stroud, D.A., Maroofian, R., Christodoulou, J., Gustafsson, C., Nalini, A., Lochmüller, H., Minczuk, M., Horvath, R. (2023) TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nature communications. 14:10091009

Gangfuß, A., Czech, A., Hentschel, A., Münchberg, U., Horvath, R., Töpf, A., O'Heir, E., Lochmüller, H., Stehling, F., Kiewert, C., Sickmann, A., Kuechler, A., Kaiser, F., Kölbel, H., Christiansen, J., Schara-Schmidt, U., Roos, A. (2021) Homozygous WASHC4 variant in two sisters causes a syndromic phenotype defined by dysmorphisms, intellectual disability, profound developmental disorder, and skeletal muscle involvement. The Journal of pathology. 256(1):93-107

Müller, J.S., Burns, D.T., Griffin, H., Wells, G.R., Zendah, R.A., Munro, B., Schneider, C., Horvath, R. (2020) RNA exosome mutations in pontocerebellar hypoplasia alter ribosome biogenesis and p53 levels. Life science alliance. 3(8):

Munro, B., Horvath, R., Müller, J.S. (2018) Nucleoside supplementation modulates mitochondrial DNA copy number in the dguok-/- zebrafish. Human molecular genetics. 28(5):796-803

Chaouch, A., Porcelli, V., Cox, D., Edvardson, S., Scarcia, P., De Grassi, A., Pierri, C.L., Cossins, J., Laval, S.H., Griffin, H., Müller, J.S., Evangelista, T., Töpf, A., Abicht, A., Huebner, A., von der Hagen, M., Bushby, K., Straub, V., Horvath, R., Elpeleg, O., Palace, J., Senderek, J., Beeson, D., Palmieri, L., Lochmüller, H. (2014) Mutations in the Mitochondrial Citrate Carrier SLC25A1 are Associated with Impaired Neuromuscular Transmission. Journal of neuromuscular diseases. 1:75-90