ZFIN ID: ZDB-LAB-120820-1
Tyler Lab
PI/Director: Tyler, Charles R.
Contact Person: Tyler, Charles R.
Email: G.C.Paull@ex.ac.uk
URL:
Address: Biosciences, College of Life and Environmental Sciences University of Exeter Exeter EX4 4QD
Country: United Kingdom
Phone: +44 (0) 1392 723792
Fax:
Line Designation: uex


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 6 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Lee, Okhyun Post-Doc


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Mourabit, S., Fitzgerald, J.A., Ellis, R.P., Takesono, A., Porteus, C.S., Trznadel, M., Metz, J., Winter, M.J., Kudoh, T., Tyler, C.R. (2019) New insights into organ-specific oxidative stress mechanisms using a novel biosensor zebrafish. Environment International. 133:105138
Parsons, A., Lange, A., Hutchinson, T.H., Miyagawa, S., Iguchi, T., Kudoh, T., Tyler, C.R. (2019) Molecular mechanisms and tissue targets of brominated flame retardants, BDE-47 and TBBPA, in embryo-larval life stages of zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 209:99-112
Brown, A.R., Green, J.M., Moreman, J., Gunnarsson, L., Mourabit, S., Ball, J., Winter, M., Trznadel, M., Correia, A., Hacker, C., Perry, A., Wood, M., Hetheridge, M., Currie, R., Tyler, C.R. (2018) Cardiovascular effects and molecular mechanisms of bisphenol A and its metabolite MBP in zebrafish. Environmental science & technology. 53(1):463-474
Lee, C.J., Paull, G.C., Tyler, C.R. (2018) Effects of environmental enrichment on survivorship, growth, sex ratio and behaviour in laboratory maintained zebrafish Danio rerio. Journal of Fish Biology. 94(1):86-95
Ogino, Y., Tohyama, S., Kohno, S., Toyota, K., Yamada, G., Yatsu, R., Kobayashi, T., Tatarazako, N., Sato, T., Matsubara, H., Lange, A., Tyler, C.R., Katsu, Y., Iguchi, T., Miyagawa, S. (2018) Functional distinctions associated with the diversity of sex steroid hormone receptors ESR and AR. The Journal of steroid biochemistry and molecular biology. 184:38-46
Winter, M.J., Windell, D., Metz, J., Matthews, P., Pinion, J., Brown, J.T., Hetheridge, M.J., Ball, J.S., Owen, S.F., Redfern, W.S., Moger, J., Randall, A.D., Tyler, C.R. (2018) Author Correction: 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Scientific Reports. 8:15903
Moreman, J., Takesono, A., Trznadel, M., Winter, M., Perry, A., Wood, M., Rogers, N.J., Kudoh, T., Tyler, C.R. (2018) Estrogenic mechanisms and cardiac responses following early life exposure to Bisphenol A (BPA) and its metabolite 4-methyl-2,4-bis(p-hydroxyphenyl)pent-1-ene (MBP) in zebrafish. Environmental science & technology. 52(11):6656-6665
Green, J.M., Lange, A., Scott, A., Trznadel, M., Wai, H.A., Takesono, A., Brown, A.R., Owen, S.F., Kudoh, T., Tyler, C.R. (2018) Early life exposure to ethinylestradiol enhances subsequent responses to environmental estrogens measured in a novel transgenic zebrafish. Scientific Reports. 8:2699
Johnston, H.J., Verdon, R., Gillies, S., Brown, D.M., Fernandes, T.F., Henry, T.B., Rossi, A.G., Tran, L., Tucker, C., Tyler, C.R., Stone, V. (2017) Adoption of in vitro systems and zebrafish embryos as alternative models for reducing rodent use in assessments of immunological and oxidative stress responses to nanomaterials. Critical reviews in toxicology. 48(3):252-271
Moreman, J., Lee, O., Trznadel, M., David, A., Kudoh, T., Tyler, C.R. (2017) Acute toxicity, teratogenic and estrogenic effects of Bisphenol A and its alternative replacements Bisphenol S, Bisphenol F and Bisphenol AF in zebrafish embryo-larvae. Environmental science & technology. 51(21):12796-12805
Winter, M.J., Windell, D., Metz, J., Matthews, P., Pinion, J., Brown, J.T., Hetheridge, M.J., Ball, J.S., Owen, S.F., Redfern, W.S., Moger, J., Randall, A.D., Tyler, C.R. (2017) 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Scientific Reports. 7:6581
Osborne, O.J., Mukaigasa, K., Nakajima, H., Stolpe, B., Romer, I., Philips, U., Lynch, I., Mourabit, S., Hirose, S., Lead, J.R., Kobayashi, M., Kudoh, T., Tyler, C.R. (2016) Sensory systems and ionocytes are targets for silver nanoparticle effects in fish. Nanotoxicology. 10(9):1276-86
Green, J.M., Metz, J., Lee, O., Trznadel, M., Takesono, A., Brown, A.R., Owen, S.F., Kudoh, T., Tyler, C.R. (2016) High-Content and Semi-Automated Quantification of Responses to Estrogenic Chemicals Using a Novel Translucent Transgenic Zebrafish. Environmental science & technology. 50(12):6536-45
Song, L., Vijver, M.G., Peijnenburg, W.J., Galloway, T.S., Tyler, C.R. (2015) A comparative analysis on the in vivo toxicity of copper nanoparticles in three species of freshwater fish. Chemosphere. 139:181-189
Hamilton, P.B., Cowx, I.G., Oleksiak, M.F., Griffiths, A.M., Grahn, M., Stevens, J.R., Carvalho, G.R., Nicol, E., and Tyler, C. (2015) Population‐level consequences for wild fish exposed to sublethal concentrations of chemicals – a critical review. Fish and Fisheries. 17:545-566
Brown, A.R., Owen, S.F., Peters, J., Zhang, Y., Soffker, M., Paull, G.C., Hosken, D.J., Wahab, M.A., Tyler, C.R. (2015) Climate change and pollution speed declines in zebrafish populations. Proceedings of the National Academy of Sciences of the United States of America. 112(11):E1237-46
Lee, O., Green, J.M., Tyler, C.R. (2015) Transgenic fish systems and their application in ecotoxicology. Critical reviews in toxicology. 45(2):124-41
Brown, A.R., Gunnarsson, L., Kristiansson, E., Tyler, C.R. (2014) Assessing variation in the potential susceptibility of fish to pharmaceuticals, considering evolutionary differences in their physiology and ecology. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 369(1656):2411-23
Filby, A.L., Ortiz-Zarragoitia, M., and Tyler, C.R. (2014) The vas::egfp transgenic zebrafish: A practical model for studies on the molecular mechanisms by which environmental estrogens affect gonadal sex differentiation. Environmental toxicology and chemistry. 33(3):602-5
Osborne, O.J., Johnston, B., Moger, J., Baalousha, M., Lead, J., Kudoh, T., and Tyler, C. (2013) Effects of particle size and coating on nanoscale Ag and TiO2 exposure in zebrafish (Danio rerio) embryos. Nanotoxicology. 7:1315-24
van Aerle, R., Lange, A., Moorhouse, A., Paszkiewicz, K., Ball, K., Johnston, B.D., de-Bastos, E., Booth, T., Tyler, C.R., and Santos, E.M. (2013) Molecular Mechanisms of Toxicity of Silver Nanoparticles in Zebrafish Embryos. Environmental science & technology. 47(14):8005-14
Bickley, L.K., Brown, A.R., Hosken, D.J., Hamilton, P.B., Le Page, G., Paull, G.C., Owen, S.F., and Tyler, C.R. (2013) Interactive effects of inbreeding and endocrine disruption on reproduction in a model laboratory fish. Evolutionary Applications. 6(2):279-289
Söffker, M., Stevens, J.R., and Tyler, C.R. (2012) Comparative Breeding and Behavioral Responses to Ethinylestradiol Exposure in Wild and Laboratory Maintained Zebrafish (Danio rerio) Populations. Environmental science & technology. 46(20):11377-11383
Brown, A.R., Bickley, L.K., Ryan, T.A., Paull, G.C., Hamilton, P.B., Owen, S.F., Sharpe, A.D., and Tyler, C.R. (2012) Differences in sexual development in inbred and outbred zebrafish (Danio rerio) and implications for chemical testing. Aquatic toxicology (Amsterdam, Netherlands). 112-113C:27-38