ZFIN ID: ZDB-LAB-110923-2
PKU Zebrafish Functional Genomics Group
PI/Director: Zhang, Bo
Contact Person: Zhang, Bo
Email: bzhang@pku.edu.cn
URL:
Address: College of Life Sciences, Peking University, No 5 YiHeYuan Rd., Haidian District, Beijing, 100871, P. R. China
Country: China
Phone: 86-10-62759072
Fax:
Line Designation: pku


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 14 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Hu, Yingying Graduate Student Huang, Peng Graduate Student Li, Wenyuan Graduate Student
Liang, Wei Graduate Student Liu, Xinxing Graduate Student Luo, Zhou Graduate Student
Wang, Zhanxiang Graduate Student Wu, Qian Graduate Student Xia, Zhidan Graduate Student
Xiao, An Graduate Student Xu, Linjie Graduate Student Zhang, Ying Graduate Student
Zheng, Naizhong Graduate Student Zu, Yao Graduate Student Shen, Yan Research Staff
Tong, Xiangjun Research Staff Gao, Yuying Technical Staff Zhang, Jiao Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Zhao, J., Xu, T., Yin, D., Zhang, B., Bai, J. (2017) The Regulatory Roles of MicroRNA in Effects of 2,2'4,4'-Tetrabromodiphenyl Ether (BDE47) on the Transcriptome of Zebrafish Larvae. PLoS One. 12:e0169599
Yan, Q., Zhai, L., Zhang, B., Dallman, J.E. (2016) Spatial patterning of excitatory and inhibitory neuropil territories during spinal circuit development. The Journal of comparative neurology.
Deng, M., Zhang, Y., Quan, X., Na, C., Chen, S., Liu, W., Han, S., Masunaga, S. (2016) Acute toxicity reduction and toxicity identification in pigment-contaminated wastewater during anaerobic-anoxic-oxic (A/A/O) treatment process. Chemosphere. 168:1285-1292
Zhang, Y., Ma, J., Shi, L., Cao, D., Quan, X. (2016) Joint toxicity of cadmium and SDBS on Daphnia magna and Danio rerio. Ecotoxicology (London, England). 25(10):1703-1711
Huang, P., Xiao, A., Tong, X., Lin, S., Zhang, B. (2016) Targeted Mutagenesis in Zebrafish by TALENs. Methods in molecular biology (Clifton, N.J.). 1338:191-206
Zhang, J., Wang, C., Shen, Y., Chen, N., Wang, L., Liang, L., Guo, T., Yin, X., Ma, Z., Zhang, B., Yang, L. (2016) A mutation in ADIPOR1 causes nonsyndromic autosomal dominant retinitis pigmentosa. Human genetics. 135(12):1375-1387
Li, W., Zheng, N.Z., Yuan, Q., Xu, K., Yang, F., Gu, L., Zheng, G.Y., Luo, G.J., Fan, C., Ji, G.J., Zhang, B., Cao, H., Tian, X.L. (2016) NFAT5-mediated CACNA1C expression is critical for cardiac electrophysiological development and maturation. J. Mol. Med.. 94(9):993-1002
Xiao, A., Zhang, B. (2016) Generation of Targeted Genomic Deletions Through CRISPR/Cas System in Zebrafish. Methods in molecular biology (Clifton, N.J.). 1451:65-79
Zhang, Y., Huang, H., Zhang, B., Lin, S. (2016) TALEN- and CRISPR-enhanced DNA homologous recombination for gene editing in zebrafish. Methods in cell biology. 135:107-20
Na, C., Zhang, Y., Deng, M., Quan, X., Chen, S., Zhang, Y. (2016) Evaluation of the detoxication efficiencies for acrylonitrile wastewater treated by a combined anaerobic oxic-aerobic biological fluidized tank (A/O-ABFT) process: Acute toxicity and zebrafish embryo toxicity. Chemosphere. 154:1-7
Cox, J.A., Zhang, B., Pope, H.M., Voigt, M.M. (2016) Transcriptome Analysis of Chemically-Induced Sensory Neuron Ablation in Zebrafish. PLoS One. 11:e0148726
Tao, X., Li, C., Zhang, B., He, Y. (2015) Effects of aqueous stable fullerene nanocrystals (nC60) on the food conversion from Daphnia magna to Danio rerio in a simplified freshwater food chain. Chemosphere. 145:157-162
Dong, X., Chen, B., Zhang, Y., Zu, Y., Li, W., Zhang, Q. (2015) Zebrafish as a useful model for zoonotic Vibrio parahaemolyticus pathogenicity in fish and human. Developmental and comparative immunology. 55:159-68
Zhang, Y., Ma, J., Zhou, S., Ma, F. (2015) Concentration-dependent toxicity effect of SDBS on swimming behavior of freshwater fishes. Environmental Toxicology and Pharmacology. 40:77-85
Liu, H.J., Zhang, C.Y., Song, F., Xiao, T., Meng, J., Zhang, Q., Liang, C.L., Li, S., Wang, J., Zhang, B., Liu, Y.R., Sun, T., Zhou, H.G. (2015) A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor γ with Excellent Effect on Insulin Resistance and Type 2 Diabetes. The Journal of pharmacology and experimental therapeutics. 353:573-81
Lee, H.J., Lowdon, R.F., Maricque, B., Zhang, B., Stevens, M., Li, D., Johnson, S.L., Wang, T. (2015) Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos. Nature communications. 6:6315
Zhou, S., Watanabe, H., Wei, C., Wang, D., Zhou, J., Tatarazako, N., Masunaga, S., Zhang, Y. (2015) Reduction in toxicity of coking wastewater to aquatic organisms by vertical tubular biological reactor. Ecotoxicology and environmental safety. 115:217-222
Huang, L., Xiao, A., Wecker, A., McBride, D.A., Choi, S.Y., Zhou, W., Lipschutz, J.H. (2014) A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys. Journal of visualized experiments : JoVE. (94)
Hüsken, U., Stickney, H.L., Gestri, G., Bianco, I.H., Faro, A., Young, R.M., Roussigne, M., Hawkins, T.A., Beretta, C.A., Brinkmann, I., Paolini, A., Jacinto, R., Albadri, S., Dreosti, E., Tsalavouta, M., Schwarz, Q., Cavodeassi, F., Barth, A.K., Wen, L., Zhang, B., Blader, P., Yaksi, E., Poggi, L., Zigman, M., Lin, S., Wilson, S.W., Carl, M. (2014) Tcf7l2 Is Required for Left-Right Asymmetric Differentiation of Habenular Neurons. Current biology : CB. 24(19):2217-27
Zhang, Y., Ear, J., Yang, Z., Morimoto, K., Zhang, B., Lin, S. (2014) Defects of protein production in erythroid cells revealed in a zebrafish Diamond-Blackfan anemia model for mutation in RPS19. Cell Death & Disease. 5:e1352
Zhang, J., Chen, S., Zhang, Y., Quan, X., Zhao, H., Zhang, Y. (2014) Reduction of acute toxicity and genotoxicity of dye effluent using Fenton-coagulation process. Journal of hazardous materials. 274C:198-204
Zhao, L., Xia, Z., Wang, F. (2014) Zebrafish in the sea of mineral (iron, zinc, and copper) metabolism. Frontiers in pharmacology. 5:33
Huang, P., Xiao, A., Tong, X., Zu, Y., Wang, Z., Zhang, B. (2014) TALEN construction via "Unit Assembly" method and targeted genome modifications in zebrafish. Methods (San Diego, Calif.). 69(1):67-75
Liu, D., Wang, Z., Xiao, A., Zhang, Y., Li, W., Zu, Y., Yao, S., Lin, S., and Zhang, B. (2014) Efficient gene targeting in zebrafish mediated by a zebrafish-codon-optimized cas9 and evaluation of off-targeting effect. Journal of Genetic Genomics. 41(1):43-46
Tong, X., Zu, Y., Li, Z., Li, W., Ying, L., Yang, J., Wang, X., He, S., Liu, D., Zhu, Z., Chen, J., Lin, S., and Zhang, B. (2014) Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish. Nature communications. 5:3153
Zheng, C., Zhou, H., Liu, X., Pang, Y., Zhang, B., and Huang, Y. (2013) Fish in chips: an automated microfluidic device to study drug dynamics in vivo using zebrafish embryos. Chemical Communications. 50(8):981-984
Xia, Z., Tong, X., Liang, F., Zhang, Y., Kuok, C., Zhang, Y., Liu, X., Zhu, Z., Lin, S., and Zhang, B. (2013) Eif3ba regulates cranial neural crest development by modulating p53 in zebrafish. Developmental Biology. 381(1):83-96
Xiao, A., Wang, Z., Hu, Y., Wu, Y., Luo, Z., Yang, Z., Zu, Y., Li, W., Huang, P., Tong, X., Zhu, Z., Lin, S., and Zhang, B. (2013) Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic acids research. 41(14):e141
Jiang, L., Zhang, J., Wang, J.J., Wang, L., Zhang, L., Li, G., Yang, X., Ma, X., Sun, X., Cai, J., Zhang, J., Huang, X., Yu, M., Wang, X., Liu, F., Wu, C.I., He, C., Zhang, B., Ci, W., and Liu, J. (2013) Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. Cell. 153(4):773-784
Wang, L., Liu, T., Xu, L., Gao, Y., Wei, Y., Duan, C., Chen, G.Q., Lin, S., Patient, R., Zhang, B., Hong, D., and Liu, F. (2013) Fev regulates hematopoietic stem cell development via ERK signaling. Blood.. 122(3):367-75
Liu, X.X., Zhang, Y.T., and Zhang, B. (2013) A surgery protocol to construct zebrafish heart damage and regeneration model. Yi chuan = Hereditas. 35(4):529-532
Shen, Y., Huang, P., and Zhang, B. (2013) A protocol for TALEN construction and gene targeting in zebrafish. Yi chuan = Hereditas. 35(4):533-544
Shen, Y., Xiao, A., Huang, P., Wang, W.Y., Zhu, Z.Y., and Zhang, B. (2013) TALE nuclease engineering and targeted genome modification. Yi chuan = Hereditas. 35(4):395-409
Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
Zu, Y., Tong, X., Wang, Z., Liu, D., Pan, R., Li, Z., Hu, Y., Luo, Z., Huang, P., Wu, Q., Zhu, Z., Zhang, B., and Lin, S. (2013) TALEN-mediated precise genome modification by homologous recombination in zebrafish. Nature Methods. 10(4):329-31
Tong, X., Xia, Z., Zu, Y., Telfer, H., Hu, J., Yu, J., Liu, H., Zhang, Q., Sodmergen, D., Lin, S., and Zhang, B. (2013) Ngs (notochord granular surface) encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish. The Journal of biological chemistry. 288(4):2711-2720
Huang, P., Xu, L., Liang, W., Tam, C.I., Zhang, Y., Qi, F., Zhu, Z., Lin, S., and Zhang, B. (2013) Genomic deletion induced by Tol2 transposon excision in zebrafish. Nucleic acids research. 41(2):e36
Dong, W., Yang, Z., Yang, F., Wang, J., Zhuang, Y., Xu, C., Zhang, B., Tian, X.L., and Liu, D. (2012) Suppression of rap1 impairs cardiac myofibrils and conduction system in zebrafish. PLoS One. 7(11):e50960
Huang, P., Zhu, Z., Lin, S., and Zhang, B. (2012) Reverse genetic approaches in zebrafish. Journal of Genetic Genomics. 39(9):421-433
Mu, Y., Li, X.Q., Zhang, B., and Du, J.L. (2012) Visual Input Modulates Audiomotor Function via Hypothalamic Dopaminergic Neurons through a Cooperative Mechanism. Neuron. 75(4):688-699
Shao, M., Lin, Y., Liu, Z., Zhang, Y., Wang, L., Liu, C., and Zhang, H. (2012) GSK-3 Activity Is Critical for the Orientation of the Cortical Microtubules and the Dorsoventral Axis Determination in Zebrafish Embryos. PLoS One. 7(5):e36655
Zhang, Y., Morimoto, K., Danilova, N., Zhang, B., and Lin, S. (2012) Zebrafish Models for Dyskeratosis Congenita Reveal Critical Roles of p53 Activation Contributing to Hematopoietic Defects through RNA Processing. PLoS One. 7(1):e30188
Gao, W., Xu, L., Guan, R., Liu, X., Han, Y., Wu, Q., Xiao, Y., Qi, F., Zhu, Z., Lin, S., and Zhang, B. (2011) Wdr18 Is Required for Kupffer's Vesicle Formation and Regulation of Body Asymmetry in Zebrafish. PLoS One. 6(8):e23386
Huang, P., Xiao, A., Zhou, M., Zhu, Z., Lin, S., and Zhang, B. (2011) Heritable gene targeting in zebrafish using customized TALENs. Nat. Biotechnol.. 29(8):699-700
Jin, M., Zhang, Y., Ye, J., Huang, C., Zhao, M., and Liu, W. (2010) Dual enantioselective effect of the insecticide bifenthrin on locomotor behavior and development in embryonic-larval zebrafish. Environmental toxicology and chemistry. 29(7):1561-1567
Zhang, Y., Shao, M., Wang, L., Liu, Z., Gao, M., Liu, C., and Zhang, H. (2010) Ethanol exposure affects cell movement during gastrulation and induces split axes in zebrafish embryos. Int. J. Dev. Neurosci.. 28(4):283-288
Jin, M., Zhang, X., Wang, L., Huang, C., Zhang, Y., and Zhao, M. (2009) Developmental toxicity of bifenthrin in embryo-larval stages of zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 95(4):347-354
Wen, L., Wei, W., Gu, W., Huang, P., Ren, X., Zhang, Z., Zhu, Z., Lin, S., and Zhang, B. (2008) Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish. Developmental Biology. 314(1):84-92
Wang, L., Zhang, Y., Shao, M., and Zhang, H. (2007) Spatiotemporal expression of the creatine metabolism related genes agat, gamt and ct1 during zebrafish embryogenesis. The International journal of developmental biology. 51(3):247-253