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Fig. S3
Transient induction of kRASG12V at an early stage resulted in developmental and tumorigenic defects. An early administration of cyclofen at the one-cell stage caused severe developmental defects in 5 dpf fish (A) compared to non-treated control (B). Many fish also exhibited tumorigenic and hyperplasic tissues (C) with remaining CFP expression (D, E zoom-in images of C). Scale bar: 200 μm.
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