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Fig. 11

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ZDB-IMAGE-170512-10
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Figures for Chetty et al., 2017
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Figure Caption

Fig. 11

Arterial marker expression is restored by etv2 overexpression in vegfaa mutant embryos. In situ hybridization analysis of arterial cldn5b expression at 24 hpf. vegfaa mutant embryos and wild-type siblings were injected with fli1a:etv2-2A-mCherry DNA overexpression construct together with tol2 mRNA. Note the absent cldn5b expression in vegfaa-/- embryos (C) and restored and expanded cldn5b expression in (D). ISV sprouting was not rescued in fli1:etv2-mCherry; vegfaa-/- embryos.

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Reprinted from Developmental Biology, 424(2), Chetty, S.C., Rost, M.S., Enriquez, J.R., Schumacher, J.A., Baltrunaite, K., Rossi, A., Stainier, D.Y., Sumanas, S., Vegf Signaling Promotes Vascular Endothelial Differentiation by Modulating etv2 Expression, 147-161, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.