ZFIN Image: Kamel et al., 2013, Fig. 4

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Figure Caption

Fig. 4 frzb and fzd7a are required for palatal extension. Anterior is to the left in all views. (A–F) Photoconversion was performed unilaterally, with the contralateral side serving as internal control. Wildtype trabeculae/maxillary prominence was photoconverted at 55 hpf and followed through 4.5 dpf, where the paired maxillary process CNCCs converge in the midline (asterisk) and extend (bracket) with distal proliferative front (bar). In frzb and fzd7a morphants, paired maxillary process converged in the midline (asterisk in E, F) but failed to extend (brackets in E and F are shorter than in D) and the proliferative domain is diminished in the distal portion of the palate (bars in E and F are shorter than in D).

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Acknowledgments

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Reprinted from Developmental Biology, 381(2), Kamel, G., Hoyos, T., Rochard, L., Dougherty, M., Tse, W., Shubinets, V., Grimaldi, M., and Liao, E.C., Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis, 423-33, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.