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Fig. S10
Blastula transplant controls.
(A) Uninjected control cmyb:GFP embryo.
(B) Uninjected control lmo2:dsRed embryo.
(C) Recipient cmyb:GFP embryos injected with nos1 MO had a grossly normal phenotype normal and express cmyb:GFP robustly in the eye, and neural crest; greatly reduced expression was found in the HSC compartment. Donor-derived endothelial cells could be seen in red fluorescence.
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Reprinted from Cell, 137(4), North, T.E., Goessling, W., Peeters, M., Li, P., Ceol, C., Lord, A.M., Weber, G.J., Harris, J., Cutting, C.C., Huang, P., Dzierzak, E., and Zon, L.I., Hematopoietic stem cell development is dependent on blood flow, 736-748, Copyright (2009) with permission from Elsevier. Full text @ Cell