ZFIN Image: Huang et al., 2003, Fig. 9

Image

Figure Caption

Fig. 9 Branching defects in developing caudal veins in reg6 embryos. (A) A wild-type TG(fli1:EGFP)^y1 embryo at 30 h postfertilization (hpf) (33°C) shows numerous branches (yellow arrows) in the developing caudal vein. (B) These branches develop into a plexus within a few hours and the plexus persists for several days during embryogenesis (a 40-hpf embryo is shown). (C) Bright field image of (B). (D) The developing caudal vein in reg6;TG(fli1:EGFP)^y1 embryo at 30 hpf (33°C) shows fewer branches (yellow arrow) and a developing sinus (red arrow). (E) By 40 hpf, the developing caudal veins in reg6;TG(fli1:EGFP)^y1 embryos become swollen and form a sinus (red arrow). (F) Bright field image of (E); red arrow, developing sinus. Anterior to the left and dorsal up. hpf, hour post fertilization. Scale bars, 100 μm.

Acknowledgments

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Reprinted from Developmental Biology, 264(1), Huang, C., Lawson, N.D., Weinstein, B.M., and Johnson, S.L., reg6 is required for branching morphogenesis during blood vessel regeneration in zebrafish caudal fins, 263-274, Copyright (2003) with permission from Elsevier. Full text @ Dev. Biol.