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Fig. 1

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ZDB-IMAGE-070925-123
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Figures for Oates et al., 2005
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Fig. 1 Gene expression defects in the paraxial mesoderm of fused somites/tbx24 mutant embryos. Expression of (A) mespb, (B) papc, (C) fgf8, and (D) myoD mRNA in paraxial mesoderm and tailbud of wild-type (left panel) and fss/tbx24 mutant (right panel) embryos at 5–6 (A, B) and 10 (C, D) somite stages. Embryos are deyolked and flat mounted with anterior up. Arrowheads indicate somitic boundaries. (E–F) Comparison of notch5 expression in wild type and fss/tbx24 backgrounds at the 5 somite stage. (E) Expression of notch5 mRNA in caudal half of PM segments. From left to right, panels show cell nuclei, notch5 expression, and a merge of the two. (F) Paraxial notch5 expression is absent from fss/tbx24 mutant embryos, although retained in the notochord and intermediate mesoderm.

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Reprinted from Developmental Biology, 283(1), Oates, A.C., Rohde, L.A., and Ho, R.K., Generation of segment polarity in the paraxial mesoderm of the zebrafish through a T-box-dependent inductive event, 204-214, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.