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ZIRC
ZFIN ID: ZDB-GENE-990726-27
Gene Name: T-box transcription factor 2b
Gene Symbol: tbx2b
Sequence Ontology ID : SO:0000704

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Previous Names: tbx-c, tbx2, tbxc, fby, hm:zeh1581 (1), lor, zeh1581

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II activating transcription factor binding activity; and RNA polymerase II regulatory region  ...
GENE EXPRESSION
All Expression Data: 80 figures from 56 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [MGC:55196]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
c144 Point Mutation Unknown Premature Stop ENU
la019280Tg Transgenic Insertion Unknown Unknown DNA
la019281Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • p25bbtl Unknown Unknown Unknown ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH tbx2b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Vertebral anomalies and variable endocrine and T-cell dysfunction 618223
    Vertebral anomalies and variable endocrine and T-cell dysfunction 618223
    DISEASE ASSOCIATED WITH tbx2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axial mesoderm development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 34)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tbx2b-201 (1) 2616
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    MARKER RELATIONSHIPS
    tbx2bContained in: [BAC] CH211-229G11 (1) (order this)
    tbx2bEncodes: [EST] zeh1581
    [cDNA] MGC:55196 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131051 (1) 2628bp
    Genomic GenBank:AL954322 (1) 149122bp
    Select Tool
    Polypeptide UniProtKB:Q7ZTU9 (1) 687aa
    Sequence Clusters UniGene:8233 (1)
    Sequence Information (all 19)
    ORTHOLOGY for tbx2b (Chr: 15)
    CITATIONS (128)