ZFIN ID: ZDB-GENE-990415-98
Gene Name: homeobox A2b
Gene Symbol: hoxa2b
Sequence Ontology ID : SO:0000704

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Previous Names: hoxa2, etID309949.16 (1), Z-75

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity; predicted to be involved in several processes,  ...
GENE EXPRESSION
All Expression Data: 42 figures from 33 publications
Directly Submitted Expression Data: 6 figures (16 images) from Thisse et al., 2005 [eu715]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36100 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hoxa2b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Microtia with or without hearing impairment (AD) 612290
    ?Microtia, hearing impairment, and cleft palate (AR) 612290
    DISEASE ASSOCIATED WITH hoxa2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001827 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00032 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hoxa2b-201 (1) 1914
    ottdart00000001850 (1) 1797
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM hoxa2b
    MARKER RELATIONSHIPS
    hoxa2bContained in: [BAC] DKEY-45E15 (1) (order this)
    [PAC] BUSM1-31B14 (1) (order this)
    hoxa2bEncodes: [EST] eu715 (1)
    [cDNA] MGC:193940 (1) (order this), MGC:193947 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131106 (1) 1797bp
    Genomic GenBank:CR392024 (1) 183486bp
    Select Tool
    Polypeptide UniProtKB:B3DG99 (1) 363aa
    Sequence Clusters UniGene:82597 (1)
    Sequence Information (all 29)
    OTHER hoxa2b GENE PAGES
  • Alliance (1)
  • Gene:30325 (1)
  • VEGA:OTTDARG00000001732 (1)
  • VEGA:OTTDARG00000027661 (1)
  • Ensembl(GRCz11):ENSDARG00000023031 (2)
  • ORTHOLOGY for hoxa2b (Chr: 16)
    CITATIONS (96)