Gene

tpma

ID
ZDB-GENE-990415-269
Name
alpha-tropomyosin
Symbol
tpma Nomenclature History
Previous Names
  • tm
  • fb37a09
  • TPM1-2 alpha (1)
  • tropomyosin alpha chain
  • wu:fb37a09 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in myeloid cell development. Predicted to localize to actin filament. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1Y; familial hypertrophic cardiomyopathy; hypertrophic cardiomyopathy 3; and nemaline myopathy 1. Is expressed in adaxial cell; male organism; musculature system; pericardial region; and somite. Orthologous to several human genes including TPM1 (tropomyosin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
37 figures from 26 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Gieger et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tpma Human Ortholog
No data available
Associated With tpma Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000533 Tropomyosin
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations