ZFIN ID: ZDB-GENE-990415-22
Gene Name: dharma
Gene Symbol: dharma    Nomenclature History

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Previous Names: dha (1), boz, bozozok, momo, nieuwkoid, nwk

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ morphogenesis; floor plate development; and regulation of signal transduction. Predicted to localize to nucleus. Is expressed in embryonic structure.
Genome Resources: Alliance (1),  Gene:30170 (1),  Ensembl(GRCz11):ENSDARG00000040955 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
i2 Unknown Unknown Unknown
m168 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • th211 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dharma N/A 1
    MO2-dharma N/A 2
    DISEASE ASSOCIATED WITH dharma HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dharma VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of fibroblast growth factor receptor signaling pathway (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dharma-201 (1)    Ensembl 770
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM dharma
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(dharma:GFP) dharma GFP Danio rerio 1 5
    MARKER RELATIONSHIPS
    dharma Contained in: [BAC] CH211-188J1 (1)
    dharma Contains: [SNP] rs3728729 (1), rs3728730 (1), rs3728731 (1), rs3728732 (1), rs3728733 (1), rs3728734 (1)
    dharma Encodes: [cDNA] MGC:152854 (1), MGC:192346 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_130979 (1) 835 nt
    Genomic GenBank:CR388133 (1) 98273 nt
    Select Tool
    Polypeptide UniProtKB:B2GRU4 (1) 192 aa
    Sequence Information (all 20)
    ORTHOLOGY for dharma ( Chr: 15 )
    CITATIONS (153)