Gene
mxi1
- ID
- ZDB-GENE-990415-151
- Name
- max interactor 1, dimerization protein
- Symbol
- mxi1 Nomenclature History
- Previous Names
-
- etID309773.22 (1)
- fb16b12
- fb55f03
- wu:fb16b12
- wu:fb55f03
- wu:fd06a08
- wu:fz74f10
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity and protein dimerization activity. Predicted to localize to nucleus. Is expressed in several structures, including axial chorda mesoderm; median fin fold; nervous system; neural tube; and periderm. Human ortholog(s) of this gene implicated in neurofibrosarcoma and prostate cancer. Orthologous to human MXI1 (MAX interactor 1, dimerization protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56456 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| prostate cancer | Alliance | Prostate cancer, somatic | 176807 |
| Neurofibrosarcoma, somatic |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|
|
UniProtKB:P50541
|
243 | ||
|
UniProtKB:A3KQG0
|
273 | ||
|
UniProtKB:Q7ZUI9
|
243 | ||
|
UniProtKB:A3KQG1
|
222 |
Interactions and Pathways
No data available
Plasmids
No data available