ZFIN ID: ZDB-GENE-980526-558
Gene Name: WT1 transcription factor a
Gene Symbol: wt1a
Sequence Ontology ID : SO:0000704

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Previous Names: wt1, zwt1

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Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription factor activity, RNA polymerase II-specific; involved in several processes, including adrenal gland development, adrenal gland development, and  ...
GENE EXPRESSION
All Expression Data: 91 figures from 55 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2005 [eu357]
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17769 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 14 figures from 8 publications
    Observed in:
    DISEASE ASSOCIATED WITH wt1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Denys-Drash syndrome Denys-Drash syndrome 194080
    Frasier syndrome Frasier syndrome 136680
    malignant mesothelioma Mesothelioma, somatic 156240
    nephroblastoma Wilms tumor, type 1 194070
    nephrotic syndrome type 4 Nephrotic syndrome, type 4 256370
    Meacham syndrome 608978
    DISEASE ASSOCIATED WITH wt1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process adrenal gland development (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000976 (1)
  • InterPro:IPR013087 (1)
  • InterPro:IPR017987 (1)
  • InterPro:IPR036236 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
  • Pfam:PF00096 (1)
  • Pfam:PF02165 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wt1a-201 (1) 1874
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM wt1a
    MARKER RELATIONSHIPS
    wt1aContained in: [BAC] CH73-152I22 (1) (order this), DKEY-114A13 (1) (order this)
    wt1aEncodes: [EST] eu357 (1)
    [cDNA] MGC:193986 (1) (order this), MGC:193994 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131046 (1) 1807bp
    Genomic GenBank:CR762411 (1) 35418bp
    Select Tool
    Polypeptide UniProtKB:Q9PUT7 (1) 419aa
    Sequence Clusters UniGene:132864 (1)
    Sequence Information (all 24)
    OTHER wt1a GENE PAGES
  • Alliance (1)
  • Gene:30245 (1)
  • VEGA:OTTDARG00000035742 (1)
  • Ensembl(GRCz11):ENSDARG00000031420 (2)
  • ORTHOLOGY for wt1a (Chr: 25)
    CITATIONS (122)