ZFIN ID: ZDB-GENE-980526-526
Gene Name: wingless-type MMTV integration site family, member 1
Gene Symbol: wnt1

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Previous Names: int-1, etID22400.23 (1), sb:eu647, zgc:194464, zgc:194478

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 94 figures from 64 publications
Directly Submitted Expression Data: 6 figures (26 images) from Thisse et al., 2005 [eu647]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  alar plate midbrain region, brain, central nervous system, cerebellum (all 57) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24353 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-wnt1 (1), MO2-wnt1 (1), MO3-wnt1 (1)
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in: cell proliferation in hindbrain, cranial nerve IX, cranial nerve VI, cranial nerve VII (all 12) expand
    DISEASE ASSOCIATED WITH wnt1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    osteogenesis imperfecta type 15 Osteogenesis imperfecta, type XV 615220
    {Osteoporosis, early-onset, susceptibility to, autosomal dominant} 615221
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process midbrain-hindbrain boundary development (more)
    Cellular Component extracellular region (more)
    Molecular Function receptor binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR009139 (1)
  • InterPro:IPR018161 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wnt1-001 (1) 1360
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM wnt1
    Tg(-6.6wnt1:GAL4-VP16-6.7wnt1,14xUAS-E1b:EGFP), Tg(wnt1:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    wnt1Contained in: [BAC] DKEY-166N8 (1) (order this)
    wnt1Encodes: [EST] eu647 (1)
    [cDNA] MGC:194464 (1) (order this), MGC:194478 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001201398 (1) 1360bp
    Genomic GenBank:CR352210 (1) 180924bp
    Select Tool
    Polypeptide UniProtKB:F1QUW0 (1) 375aa
    Sequence Clusters UniGene:85371 (1)
    Sequence Information (all 26)
    OTHER wnt1 GENE PAGES
  • Gene:30128 (1)
  • VEGA:OTTDARG00000028143 (1)
  • Ensembl(GRCz10):ENSDARG00000055554 (1)
  • ORTHOLOGY for wnt1 (Chr: 23)
    CITATIONS (147)