Gene

wnt10b

ID
ZDB-GENE-980526-524
Name
wingless-type MMTV integration site family, member 10b
Symbol
wnt10b Nomenclature History
Previous Names
  • wnt-d (1)
  • wnt10br
  • wnt[d]
  • Zwnt[d]
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have frizzled binding activity. Involved in midbrain-hindbrain boundary development. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in obesity; split hand-foot malformation 6; and tooth agenesis. Is expressed in central nervous system; neural plate; neural rod; and neural tube. Orthologous to human WNT10B (Wnt family member 10B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnt10b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
split hand-foot malformation 6 Alliance Split-hand/foot malformation 6 225300
Tooth agenesis, selective, 8 617073
Associated With wnt10b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Homologous_superfamily IPR043158 Wnt, C-terminal domain
Domain Details Per Protein
Protein Length Wnt Wnt, C-terminal domain Wnt protein, conserved site
UniProtKB:Q801F7 427
UniProtKB:B3DG58 427
UniProtKB:A0A0B5JWF2 427
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations