Gene

wnt10b

ID
ZDB-GENE-980526-524
Name
wingless-type MMTV integration site family, member 10b
Symbol
wnt10b Nomenclature History
Previous Names
  • wnt-d (1)
  • wnt10br
  • wnt[d]
  • Zwnt[d]
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have cytokine activity and frizzled binding activity. Involved in midbrain-hindbrain boundary development. Predicted to localize to extracellular space. Is expressed in central nervous system; neural plate; neural rod; and neural tube. Human ortholog(s) of this gene implicated in obesity; split hand-foot malformation 6; and tooth agenesis. Orthologous to human WNT10B (Wnt family member 10B).
Genome Resources
Note
None
Expression
All Expression Data
15 figures from 8 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnt10b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
split hand-foot malformation 6 Alliance Split-hand/foot malformation 6 225300
Tooth agenesis, selective, 8 617073
Associated With wnt10b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Homologous_superfamily IPR043158 Wnt, C-terminal domain
Domain Details Per Protein
Protein Length Wnt Wnt, C-terminal domain Wnt protein, conserved site
UniProtKB:Q801F7 427
UniProtKB:B3DG58 427
UniProtKB:A0A0B5JWF2 427
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations