ZFIN ID: ZDB-GENE-980526-52
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Gene Name: paired box 3a
Gene Symbol: pax3a
Sequence Ontology ID : SO:0000704

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Previous Names: pax3 (1), etID309899.2 (1), zgc:92547

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 60 figures from 34 publications
Directly Submitted Expression Data: 6 figures (24 images) from Thisse et al., 2004 [MGC:92547]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, central nervous system, central nervous system dorsal region (all 48) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011736Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la014990Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la014991Tg Transgenic Insertion Unknown Unknown DNA
    sa33020 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa39931 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: MO1-pax3a (1), MO2-pax3a (1), MO3-pax3a (1), MO4-pax3a (1)
    PHENOTYPE
    Data: 8 figures from 2 publications
    Observed in: cranial neural crest, cranial neural crest cell, dorsal root ganglion sensory neuron, enteric nervous system neuron neural crest derived (all 24) expand
    DISEASE ASSOCIATED WITH pax3a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    alveolar rhabdomyosarcoma Rhabdomyosarcoma 2, alveolar 268220
    Waardenburg syndrome type 1 Waardenburg syndrome, type 1 193500
    Waardenburg syndrome type 3 Waardenburg syndrome, type 3 148820
    Craniofacial-deafness-hand syndrome 122880
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process developmental pigmentation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001523 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR011991 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR022106 (1)
  • InterPro:IPR033038 (1)
    		•
  • PROSITE:PS00027 (1)
  • PROSITE:PS00034 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS51057 (1)
    		•
  • Pfam:PF00046 (1)
  • Pfam:PF00292 (1)
  • Pfam:PF12360 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pax3a-001 (1) 2713
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pax3a
    Tg(pax3a:EGFP), Tg(pax3a:KALTA4,cryaa:EGFP), TgBAC(pax3a:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    pax3aContained in: [BAC] DKEY-20F20 (1) (order this)
    pax3aEncodes: [cDNA] MGC:92547 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131277 (1) 2734bp
    Select Tool
    Genomic GenBank:BX085193 (1) 246911bp Blast at MegaBLAST
    Polypeptide UniProtKB:O57416 (1) 509aa
    Select Tool
    Sequence Clusters UniGene:75806 (1)
    Sequence Information (all 17)
    OTHER pax3a GENE PAGES
  • Gene:30532 (1)
  • VEGA:OTTDARG00000020032 (1)
  • Ensembl(GRCz10):ENSDARG00000010192 (1)
    • ORTHOLOGY for pax3a (Chr: 2)
    CITATIONS (87)